Tanaka Y, Watari T, Takai Y, Niibe H, Kita M, Shimizu T, Takahashi M, Mitomo M, Jingu K, Maehara F
Dept. of Radiology, Tokyo Metropolitan Komagome Hospital.
Gan No Rinsho. 1989 Sep;35(11):1233-9.
The patients of malignant glioma mostly consisting of anaplastic astrocytoma (AA) and glioblastoma (GM) were surveyed at the Committee for Compiling the Manual of Radiotherapy in the Treatment of Brain Tumors, organized by Japanese Association for Radiotherapy Research. Total 286 patients were treated at ten institutes during the period from January 1985 through December 1987. Numbers of cases with AA and GM were 130 and 156, respectively. Concerning the treatment volume, the medium field (50-100 cm2) was applied to 127 patients (37.4%) and the whole brain to 25 one (7.4%). The total dose was given by the range from 56 Gy to 65 Gy in 158 patients (47.6%). One-year survival ratio of AA and GM were 60-75% and 40-65%, respectively. For obtaining the improvement of local control rate, it is considered that the beam focusing onto the target lesion and the sufficient removal of the tumor are necessary and essential.
在日本放射治疗研究协会组织的脑肿瘤放射治疗手册编写委员会中,对主要由间变性星形细胞瘤(AA)和胶质母细胞瘤(GM)组成的恶性胶质瘤患者进行了调查。在1985年1月至1987年12月期间,十个机构共治疗了286例患者。AA和GM的病例数分别为130例和156例。关于治疗范围,127例患者(37.4%)采用中等野(50 - 100平方厘米),25例患者(7.4%)采用全脑照射。158例患者(47.6%)的总剂量范围为56 Gy至65 Gy。AA和GM的一年生存率分别为60 - 75%和40 - 65%。为提高局部控制率,认为将射线聚焦于靶病变以及充分切除肿瘤是必要且至关重要的。