St. George's University of London, London, United Kingdom.
Am J Cardiol. 2012 Jul 15;110(2):270-6. doi: 10.1016/j.amjcard.2012.03.021. Epub 2012 Apr 12.
The problem of early recognition of atrial fibrillation (AF) is greatly aggravated by the often silent nature of the rhythm disturbance. In about 1/3 of patients with this arrhythmia, patients are not aware of the so-called asymptomatic AF. In the past 15 years, the diagnostic data provided by implanted pacemakers and defibrillators have dramatically increased knowledge about silent AF. The unreliability of symptoms to estimate AF burden and to identify patients with and without AF has been pointed out not only by pacemaker trials but also in patients without implanted devices. The technology for continuous monitoring of AF has been largely validated. It is a powerful tool to detect silent paroxysmal AF in patients without previously documented arrhythmic episodes, such as those with cryptogenic stroke or other risk factors. Early diagnosis triggers earlier treatment for primary or secondary stroke prevention. Today, new devices are also available for pure electrocardiographic monitoring, implanted subcutaneously using a minimally invasive technique. In conclusion, this recent and promising technology adds relevant clinical and scientific information to improve risk stratification for stroke and may play an important role in testing and tailoring the therapies for rhythm and rate control.
心房颤动 (AF) 的早期识别问题因节律紊乱常常无症状而大大加剧。在约 1/3 的此类心律失常患者中,患者并未意识到所谓的无症状 AF。在过去的 15 年中,植入式起搏器和除颤器提供的诊断数据极大地增加了对无症状 AF 的认识。症状对 AF 负荷的估计以及识别有和无 AF 的患者的可靠性不仅已在起搏器试验中指出,而且在无植入装置的患者中也已指出。AF 连续监测技术已得到广泛验证。它是一种强大的工具,可在以前无记录的心律失常发作(例如隐源性中风或其他危险因素)的患者中检测无症状阵发性 AF。早期诊断可触发针对原发性或继发性中风预防的早期治疗。如今,也可使用微创技术通过皮下植入的方式,提供用于纯心电图监测的新型设备。总之,这项新的、有前途的技术为改善中风风险分层提供了相关的临床和科学信息,并可能在测试和定制节律和心率控制疗法方面发挥重要作用。