Oguri Takuya, Sugiyama Hanako, Hamano Toshiaki, Tachibana Naoko
Center for Sleep-related Disorders, Kansai Electric Power Hospital, Japan.
Intern Med. 2012;51(8):933-4. doi: 10.2169/internalmedicine.51.6853. Epub 2012 Apr 15.
We report a patient with restless legs syndrome (RLS) and chronic liver disease (CLD), whose RLS symptoms fluctuated in correlation with serum ammonia level. RLS in this patient seemed to be secondary to CLD because palliative medications for the liver dysfunction showed an additional effect on RLS symptoms that were partially controlled by levodopa. CLD should be born in mind as one of the factors to cause RLS symptoms; the therapeutic mechanism of RLS enhanced by palliative medications for CLD is discussed.
我们报告了一名患有不宁腿综合征（RLS）和慢性肝病（CLD）的患者，其RLS症状随血清氨水平波动。该患者的RLS似乎继发于CLD，因为针对肝功能障碍的姑息治疗药物对RLS症状有额外疗效，而RLS症状此前已通过左旋多巴得到部分控制。应将CLD视为导致RLS症状的因素之一；本文还讨论了针对CLD的姑息治疗药物增强RLS治疗效果的机制。
