Centre des MST, Hôpital St-Louis, AP-HP, Paris, France.
Sex Transm Dis. 2012 May;39(5):359-60. doi: 10.1097/OLQ.0b013e318249968c.
Although there is no data in the literature, some textbooks recommend fractioning the injection of benzathine penicillin G (BPG) for alleviating the pain. In a monocentric study done in 50 consecutive patients with late syphilis. Patients were assigned to receive 1 dose of 2.4 million units BPG intramuscularly the first week and 2 doses of 1.2 million units BPG in each buttock the second week. In the third week, patients were asked to choose between the 2 options. It was demonstrated that the 2 techniques were equally well tolerated and equally preferred by patients.
尽管文献中没有数据，但一些教科书建议分注苄星青霉素 G（BPG）以减轻疼痛。在一项对 50 例晚期梅毒患者进行的单中心研究中，患者被分为第一周肌肉注射 240 万单位 BPG 单次剂量，第二周每侧臀部注射 120 万单位 BPG 两次剂量。第三周，患者被要求在两种选择中进行选择。结果表明，两种技术的耐受性和患者的偏好程度相等。
