Cashman James, Bican Orhan, Patel Ravi, Jacovides Christina, Dalsey Chelsea, Parvizi Javad
Arthroplasty Fellow, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
Research Fellow, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
Surg Technol Int. 2011 Dec;21:261-6.
Obstructive sleep apnea (OSA) has been associated with increased risk for medical complications following total joint arthroplasty. Our institution employs postoperative precautions for OSA patients in an effort to minimize the impact of postoperative complications in this group. We performed this study to assess the effect of careful monitoring on postoperative complication rates in OSA patients. We identified patients with a clinically suspected or objective diagnosis of OSA who received total joint arthroplasty between January 1998 and January 2008. 1016 cases in 792 OSA patients were matched to 1016 cases in 993 control patients to compare complication rates. There were no differences between OSA and control patients in cardiovascular and respiratory complications following TJA. Patients with OSA experienced increased rates of postoperative acute renal failure when compared with controls (p = 0.02) and experienced mild desaturations (Hb O2 < 92%) (p = 0.002), but not severe desaturations (Hb O2 < 88%) (p = 0.2). We conclude that our postoperative monitoring protocols are successful in reducing postoperative complications most commonly associated with OSA. We were interested to note the increased risk for OSA patients to develop postoperative acute renal failure and believe that future study is warranted to explore the link between OSA and renal failure.
阻塞性睡眠呼吸暂停(OSA)与全关节置换术后医疗并发症风险增加相关。我们机构对OSA患者采取术后预防措施,以尽量减少该组患者术后并发症的影响。我们进行这项研究以评估密切监测对OSA患者术后并发症发生率的影响。我们确定了在1998年1月至2008年1月期间接受全关节置换术的临床疑似或确诊OSA的患者。将792例OSA患者中的1016例病例与993例对照患者中的1016例病例进行匹配,以比较并发症发生率。在全关节置换术后,OSA患者与对照患者在心血管和呼吸系统并发症方面没有差异。与对照组相比(p = 0.02),OSA患者术后急性肾衰竭发生率增加,且出现轻度血氧饱和度下降(血红蛋白氧饱和度<92%)(p = 0.002),但未出现严重血氧饱和度下降(血红蛋白氧饱和度<88%)(p = 0.2)。我们得出结论,我们的术后监测方案成功降低了与OSA最常见相关的术后并发症。我们注意到OSA患者术后发生急性肾衰竭的风险增加,并认为有必要进行进一步研究以探索OSA与肾衰竭之间的联系。