Department of Obstetrics and Gynecology, University Hospital, Tübingen, Germany.
J Perinat Med. 2012 Feb 10;40(3):277-86. doi: 10.1515/jpm.2011.139.
Cardiotocography and echocardiography are currently standard for fetal heart monitoring. However, both do not provide adequate temporal resolution to measure fetal cardiac time intervals and detect arrhythmias, which can occur during normal sinus rhythm. Fetal magnetocardiography (fMCG) is a non-invasive technique measuring magnetic signals generated by fetal heart activity. Most fMCG devices are installed in research institutions limiting the implementation of this method in a clinical setting. Several institutions made a step forward by installing devices, in particular for fetal investigations, in hospital sites to evaluate the clinical benefit. Based on instrumentation differences which can affect signal quality, there is still no established reference database for fetal cardiac time intervals. A new magnetograph dedicated to fetal recordings was implemented with improved patient comfort. The setting was optimized to establish a standard. A total of 103 healthy fetuses starting as early as possible after the first trimester were recorded and fMCG values of cardiac time intervals were compared to former studies. Data allowed high and reliable detection for all fMCG components starting at 17 weeks. The data were comparable to fMCG multicenter studies, fetal electrocardiography and neonatal ECG results and could serve as a database of norm values for further investigation of fetal arrhythmias.
胎儿心电图和超声心动图目前是胎儿心脏监测的标准方法。然而，这两种方法都不能提供足够的时间分辨率来测量胎儿心脏的时间间隔和检测心律失常，而心律失常可能在正常窦性心律期间发生。胎儿磁描记术（fMCG）是一种测量由胎儿心脏活动产生的磁信号的非侵入性技术。大多数 fMCG 设备都安装在研究机构中，限制了该方法在临床环境中的实施。一些机构已经迈出了一步，在医院场所安装设备，特别是用于胎儿检查，以评估临床效益。基于可能影响信号质量的仪器差异，仍然没有用于胎儿心脏时间间隔的既定参考数据库。专门用于胎儿记录的新磁强计已经实施，提高了患者的舒适度。为了建立标准，对设置进行了优化。总共记录了 103 名健康胎儿，最早从孕早期开始，比较了心脏时间间隔的 fMCG 值与以前的研究。数据允许从 17 周开始对所有 fMCG 成分进行高可靠性检测。这些数据与 fMCG 多中心研究、胎儿心电图和新生儿心电图结果相当，可以作为进一步研究胎儿心律失常的正常数值数据库。
