间歇性冲洗相较于连续输注可改善新生儿外周静脉留置导管的通畅性：一项前瞻性观察研究的结果。

Intermittent flushing improves cannula patency compared to continuous infusion for peripherally inserted venous catheters in newborns: results from a prospective observational study.

机构信息

Department of Pediatric Intensive Care and Neonatology, Zurich University Children's Hospital, Steinwiesstrasse, Zurich, Switzerland.

出版信息

J Perinat Med. 2012 Jan 19;40(3):311-4. doi: 10.1515/jpm-2011-1000.

DOI:10.1515/jpm-2011-1000

PMID:22505510

Abstract

AIMS

Peripheral cannulas in newborns are commonly used for intravenous treatment. However sustained maintenance of cannula patency is often difficult to achieve in this age group. This study compares the duration for which cannula patency can be maintained in newborns under continuous infusion, or an intermittent flushing regimen, with normal saline.

METHODS

A prospective observational study was conducted during a 12-month period. All newborns admitted to the 16-bed intermediate care unit, who required intravenous treatment, received either continuous peripheral infusion with 0.9% saline at an infusion rate of 2 mL/h or an intravenous cannula, which was flushed with 1 mL of 0.9% saline at least once every 24 h.

RESULTS

A total of 53 patients with 86 cannulas were included. Twenty-five (47%) patients received 41 continuous infusions. The intermittent flushing group consisted of 28 (53%) patients with 45 cannulas administered. The cannula patency was significantly longer in the intermittent flushing group (mean 62.1 vs. 92.8 h, P=0.01). The patient's underlying disease and the cannula insertion site were not related with the duration of the cannula patency.

CONCLUSIONS

Our study shows that intermittent cannula flushing is associated with improved cannula patency for peripherally inserted venous catheters in newborns.

摘要

目的

新生儿外周导管常被用于静脉治疗。然而，在这个年龄段，维持导管通畅通常很困难。本研究比较了在持续输注或间歇性冲洗方案下，生理盐水维持新生儿导管通畅的时间。

方法

在 12 个月期间进行了一项前瞻性观察研究。所有需要静脉治疗的入住 16 张床的中间护理单元的新生儿均接受以下治疗：以 2 mL/h 的输注速度输注 0.9%生理盐水的连续外周输注，或至少每 24 小时冲洗 1 毫升 0.9%生理盐水的静脉导管。

结果

共有 53 例患者，86 个导管被纳入研究。25 例（47%）患者接受 41 次连续输注。间歇性冲洗组包括 28 例（53%）患者，共使用 45 个导管。间歇性冲洗组的导管通畅时间明显更长（平均 62.1 小时 vs. 92.8 小时，P=0.01）。患者的基础疾病和导管插入部位与导管通畅时间无关。