Periodontol 2000. 2012 Jun;59(1):140-57. doi: 10.1111/j.1600-0757.2011.00438.x.
Gingival recession is a common clinical problem that can result in hypersensitivity, pain, root caries and esthetic concerns. Conventional soft tissue procedures for root coverage require an additional surgical site, thereby causing additional trauma and donor site morbidity. In addition, the grafted tissues heal by repair, with formation of long junctional epithelium with some connective tissue attachment. Guided tissue regeneration-based root coverage was thus developed in an attempt to overcome these limitations while providing comparable clinical results. This paper addresses the biologic foundation of guided tissue regeneration-based root coverage, and describes the indications and contraindications for this technique, as well as the factors that influence outcomes. The step-by-step clinical techniques utilizing collagen membranes are also described. In comparison with conventional soft tissue procedures, the benefits of guided tissue regeneration-based root coverage procedures include new attachment formation, elimination of donor site morbidity, less chair-time, and unlimited availability and uniform thickness of the product. Collagen membranes, in particular, benefit from product biocompatibility with the host, while promoting chemotaxis, hemostasis, and exchange of gas and nutrients. Such characteristics lead to better wound healing by promoting primary wound coverage, angiogenesis, space creation and maintenance, and clot stability. In conclusion, collagen membranes are a reliable alternative for use in root coverage procedures.
牙龈退缩是一种常见的临床问题，可导致过敏、疼痛、根面龋和美观问题。传统的软组织根向覆盖术需要额外的手术部位，从而导致额外的创伤和供区发病率。此外，移植组织通过修复愈合，形成具有一些结缔组织附着的长结合上皮。因此，引导组织再生根向覆盖术的发展旨在克服这些局限性，同时提供可比的临床结果。本文介绍了基于引导组织再生的根向覆盖的生物学基础，并描述了该技术的适应证和禁忌证，以及影响结果的因素。还描述了利用胶原膜的分步临床技术。与传统的软组织手术相比，基于引导组织再生的根向覆盖术的优点包括新附着形成、消除供区发病率、减少椅旁时间以及产品的无限可用性和均匀厚度。胶原膜尤其受益于产品与宿主的生物相容性，同时促进趋化作用、止血以及气体和营养物质的交换。这些特性通过促进原发性伤口覆盖、血管生成、空间的形成和维持以及血栓稳定性来促进更好的伤口愈合。总之，胶原膜是根向覆盖术的一种可靠替代方法。
