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父母就业、收入、教育程度与儿童过敏症:日本一项产前队列研究。

Parental employment, income, education and allergic disorders in children: a prebirth cohort study in Japan.

机构信息

Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

出版信息

Int J Tuberc Lung Dis. 2012 Jun;16(6):756-61. doi: 10.5588/ijtld.11.0484. Epub 2012 Apr 9.

DOI:10.5588/ijtld.11.0484
PMID:22507151
Abstract

SETTING

Epidemiological evidence on the relationship between socio-economic status and allergic disorders has been inconsistent.

OBJECTIVES

We examined the associations between maternal employment, maternal job type, household income, and paternal and maternal educational levels and the risk of allergic disorders in Japanese children aged 4.5 years.

DESIGN

Subjects were 480 mother-child pairs. Definitions of wheeze and eczema symptoms were based on criteria of the International Study of Asthma and Allergies in Childhood. Data on self-reported doctor-diagnosed asthma and atopic eczema were available.

RESULTS

Compared with children whose mothers had received less than 13 years of education, those with mothers with ≥15 years of education had a significantly increased risk of wheeze and doctor-diagnosed asthma: the adjusted ORs were respectively 2.41 (95%CI 1.18-5.17) and 2.70 (95%CI 1.03-8.08). Fifteen years or more of paternal education was independently associated with an increased risk of eczema, but not of doctor-diagnosed atopic eczema (adjusted OR 1.89, 95%CI 1.07-3.42). Mother's employment, mother's job type and household income were not related to any of the outcomes.

CONCLUSIONS

Higher maternal educational level may increase the risk of wheeze and asthma, while higher paternal educational level may increase the risk of eczema.

摘要

背景

关于社会经济地位与过敏疾病之间的关系,流行病学证据并不一致。

目的

我们研究了母亲的就业状况、母亲的工作类型、家庭收入以及父母的教育水平与 4.5 岁日本儿童过敏疾病风险之间的关联。

设计

研究对象为 480 对母婴。喘息和湿疹症状的定义基于儿童哮喘和过敏国际研究的标准。有关于经医生诊断的哮喘和特应性皮炎的数据。

结果

与母亲受教育不足 13 年的儿童相比,母亲受教育≥15 年的儿童喘息和经医生诊断的哮喘风险显著增加:调整后的 OR 分别为 2.41(95%CI 1.18-5.17)和 2.70(95%CI 1.03-8.08)。父亲受教育 15 年或以上与湿疹风险增加独立相关,但与经医生诊断的特应性皮炎无关(调整后的 OR 为 1.89,95%CI 1.07-3.42)。母亲的就业状况、母亲的工作类型和家庭收入与任何结果均无关。

结论

较高的母亲教育水平可能会增加喘息和哮喘的风险,而较高的父亲教育水平可能会增加湿疹的风险。

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