Meulenbelt J, Sangster B
National Poison Control Centre, National Institute of Public Health and Environmental Protection, Bilthoven.
Neth J Med. 1990 Oct;37(3-4):132-8.
Nitrogen dioxide is a representative of the group of compounds which may cause pulmonary symptoms after a symptom free interval. Even when there are no symptoms immediately following exposure to nitrogen dioxide, clinical observation is advisable, because severe pulmonary involvement can be the result. The present paper discusses the clinical symptoms which are observed in man after acute exposure to nitrogen dioxide, as well as the pathophysiological mechanisms involved. Practical therapeutic guidelines are given for dealing with the diagnostic difficulties concerning this type of intoxication.
二氧化氮是一类化合物的代表，这类化合物在一段无症状期后可能引发肺部症状。即使在接触二氧化氮后即刻没有症状，也建议进行临床观察，因为可能会导致严重的肺部病变。本文讨论了人体急性接触二氧化氮后观察到的临床症状，以及所涉及的病理生理机制。针对这类中毒的诊断困难给出了实际的治疗指南。
