频域光相干断层扫描在葡萄膜炎性黄斑水肿中的应用：形态学特征和预后因素。

Spectral-domain optical coherence tomography in uveitic macular edema: morphological features and prognostic factors.

机构信息

Department of Ophthalmology, Sapienza University of Rome, Rome, Italy. l.iannetti @ policlinicoumberto1.it

出版信息

Ophthalmologica. 2012;228(1):13-8. doi: 10.1159/000337234. Epub 2012 Apr 14.

DOI:10.1159/000337234

PMID:22508138

Abstract

AIM

To assess the morphological characteristics of uveitic macular edema studied with Spectralis optical coherence tomography (OCT) and to investigate the correlation between the tomographic features and visual acuity.

METHODS

71 eyes of 55 patients underwent examination with Spectralis OCT (Heidelberg Engineering, Germany). Data was correlated with logMAR best-corrected visual acuity (BCVA).

RESULTS

Two morphological patterns were observed: cystoid macular edema (CME) in 69% and diffuse macular edema in 31% of eyes. BCVA was 0.2 in CME, 0.1 in diffuse edema (p = 0.008). Foveal thickness was 413.4 ± 212 µm in CME, 311.27 ± 53 µm in diffuse edema (p = 0.03). BVCA was 0.3 in eyes with serous retinal detachment (SRD), 0.2 in eyes without SRD (p = 0.02). BCVA was 0.4 in eyes with inner segment/outer segment (IS/OS) disruption, 0.1 in eyes with integrity of the IS/OS junction (p = 0.01).

CONCLUSIONS

BCVA is negatively correlated with cystoid pattern, foveal thickening and SRD. Disruption of the IS/OS junction is associated with poor vision in uveitic macular edema.

摘要

目的

利用海德堡 Spectralis 光学相干断层扫描仪（OCT）评估葡萄膜炎性黄斑水肿的形态学特征，并探讨其与视力的相关性。

方法

对 55 例（71 只眼）葡萄膜炎患者进行 Spectralis OCT 检查，将所得数据与最佳矫正视力（BCVA）的 logMAR 值进行相关性分析。

结果

观察到两种形态学类型：69%的眼为囊样黄斑水肿（CME），31%的眼为弥漫性黄斑水肿。CME 眼的 BCVA 为 0.2，弥漫性水肿眼的 BCVA 为 0.1（p=0.008）。CME 眼的中心凹厚度为 413.4±212μm，弥漫性水肿眼的中心凹厚度为 311.27±53μm（p=0.03）。存在浆液性视网膜脱离（SRD）的眼的 BCVA 为 0.3，无 SRD 的眼的 BCVA 为 0.2（p=0.02）。IS/OS 节段中断的眼的 BCVA 为 0.4，IS/OS 连接完整的眼的 BCVA 为 0.1（p=0.01）。