Messano Giuseppe Alessio, Petti Stefano
Medico-Chirurgo-Dipartimento di Sanità Pubblica e Malattie Infettive, Sapienza Università di Roma, Italy.
Ig Sanita Pubbl. 2011 Nov-Dec;67(6):697-706.
Antibiotic resistance is an emerging public health problem especially due to the continuous use of antibiotics that selects more aggressive and resistant species. In the present study the authors determined the antibiotic sensitivity of 128 Mycoplasma hominis strains obtained from urethral swabs of male patients (mean age 36 years). The Mycoplasma IST 2 strip was used to test antibiotic susceptibility: 88% of analysed strains were found to be resistant to erythromycin and azithromycin, 75% to clarithromycin, 50% to ofloxacin and ciprofloxacin, and 12% to tetracycline. All strains were susceptible to josamycin, doxycycline and pristinamycin. Results were comparable to those of a recent study by Savarino-Mattei which also showed high resistance of M hominis to macrolide antibiotics and to ciprofloxacin and susceptibility to tetracyclines. Doxycycline is currently the antibiotic of first choice for treating M hominis infections.
抗生素耐药性是一个新出现的公共卫生问题，尤其是由于抗生素的持续使用筛选出了更具侵袭性和耐药性的菌株。在本研究中，作者测定了从男性患者（平均年龄36岁）尿道拭子中分离出的128株人型支原体菌株的抗生素敏感性。使用Mycoplasma IST 2试纸条检测抗生素敏感性：88%的分析菌株对红霉素和阿奇霉素耐药，75%对克拉霉素耐药，50%对氧氟沙星和环丙沙星耐药，12%对四环素耐药。所有菌株对交沙霉素、强力霉素和 pristinamycin敏感。结果与Savarino-Mattei最近的一项研究结果相当，该研究也显示人型支原体对大环内酯类抗生素、环丙沙星具有高耐药性，对四环素敏感。强力霉素目前是治疗人型支原体感染的首选抗生素。
