Jiang Yi, Wei Jun-Ji, Wang Ren-Zhi, Ren Zu-Yuan
Department of Neurosurgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Dec;33(6):696-700.
Hyponatremia is relatively common in patients with neurologic disorders, while its diagnosis and treatment remain controversial. Osmotic demyelination syndrome (ODS) has shown to be closely associated with hyponatremia. ODS patients often present as central pontine myelinolysis, extrapontine myelinolysis, or both. This article reviews the clinical manifestations, pathogenesis, and risk factors of ODS in patients with hyponatremia caused by neurologic disorders.
低钠血症在神经系统疾病患者中较为常见，但其诊断和治疗仍存在争议。渗透性脱髓鞘综合征（ODS）已被证明与低钠血症密切相关。ODS患者常表现为脑桥中央髓鞘溶解、脑桥外髓鞘溶解或两者皆有。本文综述了神经系统疾病所致低钠血症患者ODS的临床表现、发病机制和危险因素。
