Castillo R A, Ray R A, Yaghmai F
Departments of Obstetrics and Gynecology, Medical College of Georgia, Augusta.
Obstet Gynecol. 1989 Mar;73(3 Pt 2):459-61.
Central pontine myelinolysis, also known as osmotic demyelination syndrome, is an uncommon disorder associated with rapid correction of severe hyponatremia. We present the case of a healthy young pregnant woman with hyperemesis gravidarum who developed severe hyponatremia (serum sodium 103 mEq/L). After rapid correction of her serum sodium within 12-15 hours with a 0.9% saline solution, the patient became comatose and died of sepsis and respiratory failure. Examination of the brain showed extensive demyelination in both pontine and extrapontine areas.
中央桥脑髓鞘溶解症，也称为渗透性脱髓鞘综合征，是一种与严重低钠血症的快速纠正相关的罕见疾病。我们报告一例患有妊娠剧吐的健康年轻孕妇病例，该患者出现了严重低钠血症（血清钠103 mEq/L）。在用0.9%生理盐水在12 - 15小时内快速纠正其血清钠后，患者陷入昏迷，最终死于败血症和呼吸衰竭。脑部检查显示桥脑和脑桥外区域均有广泛的脱髓鞘病变。
