Interventional Cardiology Program, Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Catheter Cardiovasc Interv. 2012 Nov 1;80(5):840-4. doi: 10.1002/ccd.24280. Epub 2012 Apr 17.
The Impella LP 2.5 is a percutaneously implantable axial flow device designed to offer circulatory support for patients in cardiogenic shock during percutaneous coronary interventions (PCI). While most axial flow devices are associated with hemolysis, clinically relevant hemolysis with this device has not been reported. We report a case of a 66-year-old woman with hemodynamic collapse during an elective PCI who was successfully resuscitated with an Impella device. She developed marked biochemical evidence of intravascular hemolysis. This necessitated device removal which resulted in prompt resolution of the hemolysis. We advise routine measurement of biochemical markers of hemolysis and serial hemoglobin values during Impella device support to allow timely detection and treatment of this important complication.
Impella LP 2.5 是一种经皮植入式轴流装置，旨在为经皮冠状动脉介入治疗（PCI）期间心源性休克患者提供循环支持。虽然大多数轴流装置与溶血有关，但该装置尚未报道有临床相关的溶血。我们报告了一例 66 岁女性在选择性 PCI 期间发生血流动力学崩溃，使用 Impella 装置成功复苏。她出现了明显的血管内溶血的生化证据。这需要移除设备，从而迅速解决溶血问题。我们建议在 Impella 设备支持期间常规测量溶血的生化标志物和连续血红蛋白值，以便及时发现和治疗这种重要的并发症。
