9-（2-羟乙氧甲基）鸟嘌呤作为单纯疱疹病毒复制的抑制剂
9-(2-hydroxyethoxymethyl)guanine as an inhibitor of herpes simplex virus replication.
作者信息
Centifanto Y M, Kaufman H E
出版信息
Chemotherapy. 1979;25(5):279-81. doi: 10.1159/000237851.
PMID:225135
Abstract
The drug 9-(2-hydroxyethoxymethyl)guanine effectively inhibits herpes simplex virus replication. It is selectively phosphorylated by the virus-induced thymidine kinase but not by normal cellular thymidine kinase.
摘要
药物9-(2-羟乙氧甲基)鸟嘌呤可有效抑制单纯疱疹病毒复制。它被病毒诱导的胸苷激酶选择性磷酸化，而不会被正常细胞的胸苷激酶磷酸化。
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