Olivry T, Prélaud P, Héripret D, Atlee B A
Service de Médicine, Clinique Vétérinaire Frégis, France.
Vet Clin North Am Small Anim Pract. 1990 Nov;20(6):1443-56. doi: 10.1016/s0195-5616(90)50154-0.
Allergic contact dermatitis is a rare hypersensitivity disorder in the dog. Clinical diagnosis is not easy. Primary lesions are transient. Secondary lesions caused by chronic inflammation and self-trauma are commonly present on typical areas, especially in sparsely haired regions and on the feet. A presumptive diagnosis can be made based on the history, clinical signs, and positive standardized closed patch testing. Histopathology and basophil degranulation testing may also be helpful in supporting the diagnosis and in identifying the offending allergens. However, a definitive diagnosis can be made only after restriction-provocation testing. With better understanding of the pathogenesis and clinical signs, and with increased availability of diagnostic tests (especially a standardized closed patch test), increased recognition of this dermatosis is expected.
过敏性接触性皮炎在犬类中是一种罕见的超敏反应性疾病。临床诊断并不容易。原发性皮损是短暂的。由慢性炎症和自我创伤引起的继发性皮损通常出现在典型部位，尤其是在毛发稀疏的区域和足部。根据病史、临床症状以及阳性的标准化封闭斑贴试验可做出初步诊断。组织病理学检查和嗜碱性粒细胞脱颗粒试验也可能有助于支持诊断并识别致病过敏原。然而，只有在进行限制激发试验后才能做出明确诊断。随着对发病机制和临床症状的更好理解，以及诊断测试（尤其是标准化封闭斑贴试验）可用性的增加，预计对这种皮肤病的认识会有所提高。
