慢性肾病患者中风风险因素综述。
A review of risk factors for stroke in patients with chronic kidney disease.
作者信息
Saeed Fahad, Kousar Nadia, Qureshi Kamran, Laurence Thomas N
机构信息
Departments of Internal Medicine (FS, NK, KQ) and Neurology (TNL), Univerity of Illinois School of Medicine, Urbana Champaign, IL.
出版信息
J Vasc Interv Neurol. 2009 Jan;2(1):126-31.
BACKGROUND
Patients with chronic kidney disease (CKD) are at higher risk for stroke because of higher prevalence of traditional and non-traditional cardiovascular risk factors.
METHODS
We performed an extensive literature review with pre-defined keywords. We summarized the results of the studies evaluating for risk factors predisposing to stroke in CKD patients.
RESULTS
The incidence of stroke and stroke-related mortality is higher in CKD patients compared with the general population. Presence of anemia, hypoalbuminemia, malnutrition, uremia, and hyperhomocysteinemia in patients with CKD is associated with higher incidence of stroke. Hemodialysis and renal transplant patients are at higher risk of developing stroke compared with those who do not require renal replacement therapy.
CONCLUSION
The early recognition of risk factors associated with stroke in CKD population is imperative. Early interventions may potentially decrease the incidence and associated mortality of stroke in CKD patients.
背景
由于传统和非传统心血管危险因素的患病率较高，慢性肾脏病（CKD）患者发生中风的风险更高。
方法
我们使用预先定义的关键词进行了广泛的文献综述。我们总结了评估CKD患者中风易患危险因素的研究结果。
结果
与普通人群相比，CKD患者中风的发生率和与中风相关的死亡率更高。CKD患者中存在贫血、低白蛋白血症、营养不良、尿毒症和高同型半胱氨酸血症与中风发生率较高相关。与不需要肾脏替代治疗的患者相比，血液透析和肾移植患者发生中风的风险更高。
结论
必须尽早识别CKD人群中与中风相关的危险因素。早期干预可能会降低CKD患者中风的发生率和相关死亡率。
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