Extending the reach of Exendin-4: new pathways in the control of body weight and glucose homeostasis.
作者信息
Good Deborah J
机构信息
Department of Human Nutrition, Foods and Exercise, Virginia Tech, Blacksburg, Virginia 24061, USA.
出版信息
Endocrinology. 2012 May;153(5):2051-3. doi: 10.1210/en.2012-1149.
Abstract
摘要
相似文献
1
Extending the reach of Exendin-4: new pathways in the control of body weight and glucose homeostasis.拓展艾塞那肽-4的作用范围：控制体重和葡萄糖稳态的新途径。
Endocrinology. 2012 May;153(5):2051-3. doi: 10.1210/en.2012-1149.
2
Glucagon-like peptide-1 receptor agonist, exendin-4, regulates feeding-associated neuropeptides in hypothalamic neurons in vivo and in vitro.胰高血糖素样肽-1 受体激动剂，exendin-4，调节体内和体外下丘脑神经元中与摄食相关的神经肽。
Endocrinology. 2012 May;153(5):2208-22. doi: 10.1210/en.2011-1795. Epub 2012 Feb 14.
3
A physiological role of glucagon-like peptide-1 receptors in the central nervous system of Suncus murinus (house musk shrew).GLP-1 受体在东亚沙鼠中枢神经系统中的生理作用。
Eur J Pharmacol. 2011 Oct 1;668(1-2):340-6. doi: 10.1016/j.ejphar.2011.06.036. Epub 2011 Jul 6.
4
Glucagon-like peptide 1 excites hypocretin/orexin neurons by direct and indirect mechanisms: implications for viscera-mediated arousal.胰高血糖素样肽1通过直接和间接机制兴奋下丘脑泌素/食欲素神经元：对内脏介导的觉醒的影响。
J Neurosci. 2004 Sep 15;24(37):8141-52. doi: 10.1523/JNEUROSCI.1607-04.2004.
5
Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes.胰高血糖素样肽-1 受体激动剂通过抗炎作用改善 1 型糖尿病大鼠的肾脏损伤，而不降低血糖水平。
Diabetologia. 2011 Apr;54(4):965-78. doi: 10.1007/s00125-010-2028-x. Epub 2011 Jan 21.
6
Differences in acute anorectic effects of long-acting GLP-1 receptor agonists in rats.长效胰高血糖素样肽-1受体激动剂对大鼠急性厌食作用的差异
Peptides. 2014 Aug;58:1-6. doi: 10.1016/j.peptides.2014.05.008. Epub 2014 May 29.
7
Long-term metabolic benefits of exenatide in mice are mediated solely via the known glucagon-like peptide 1 receptor.在小鼠中，艾塞那肽的长期代谢益处仅通过已知的胰高血糖素样肽 1 受体介导。
Am J Physiol Regul Integr Comp Physiol. 2014 Apr 1;306(7):R490-8. doi: 10.1152/ajpregu.00495.2013. Epub 2014 Jan 29.
8
Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line.Exendin-4，一种胰高血糖素样肽-1 受体激动剂，可抑制脂毒性诱导的胰岛β细胞系细胞凋亡。
Peptides. 2012 Sep;37(1):18-24. doi: 10.1016/j.peptides.2012.06.018. Epub 2012 Jul 7.
9
Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.使用胰高血糖素样肽-1受体激动剂或二肽基肽酶-IV抑制剂治疗2型糖尿病。
Expert Opin Emerg Drugs. 2004 May;9(1):155-66. doi: 10.1517/eoed.9.1.155.32952.
10
Cyclic AMP-mediated pleiotropic effects of glucagon-like peptide-1 receptor activation. Focus on "Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a".胰高血糖素样肽-1受体激活的环磷酸腺苷介导的多效性作用。聚焦于“艾塞那肽-4通过抑制内质网应激和激活肌浆网钙ATP酶2a减轻高糖诱导的心肌细胞凋亡”
Am J Physiol Cell Physiol. 2013 Mar;304(6):C505-7. doi: 10.1152/ajpcell.00419.2012. Epub 2013 Jan 30.
本文引用的文献
1
Glucagon-like peptide-1 receptor agonist, exendin-4, regulates feeding-associated neuropeptides in hypothalamic neurons in vivo and in vitro.胰高血糖素样肽-1 受体激动剂，exendin-4，调节体内和体外下丘脑神经元中与摄食相关的神经肽。
Endocrinology. 2012 May;153(5):2208-22. doi: 10.1210/en.2011-1795. Epub 2012 Feb 14.
2
Anorexigenic effects of GLP-1 and its analogues.胰高血糖素样肽-1及其类似物的食欲抑制作用。
Handb Exp Pharmacol. 2012(209):185-207. doi: 10.1007/978-3-642-24716-3_8.
3
Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice.肥胖小鼠弓状核能量平衡回路的重塑受到抑制。
J Clin Invest. 2012 Jan;122(1):142-52. doi: 10.1172/JCI43134. Epub 2011 Dec 27.
4
Activation of the GLP-1 receptor signalling pathway: a relevant strategy to repair a deficient beta-cell mass.胰高血糖素样肽-1受体信号通路的激活：修复β细胞质量不足的相关策略。
Exp Diabetes Res. 2011;2011:376509. doi: 10.1155/2011/376509. Epub 2011 May 22.
5
GLP-1 and energy balance: an integrated model of short-term and long-term control.GLP-1 与能量平衡：短期和长期控制的综合模型。
Nat Rev Endocrinol. 2011 Jun 7;7(9):507-16. doi: 10.1038/nrendo.2011.77.
6
The development of Byetta (exenatide) from the venom of the Gila monster as an anti-diabetic agent.从希拉毒蜥毒液中开发出治疗糖尿病的药物百泌达（艾塞那肽）。
Toxicon. 2012 Mar 15;59(4):464-71. doi: 10.1016/j.toxicon.2010.12.016. Epub 2010 Dec 29.
7
The role of GLP-1 in neuronal activity and neurodegeneration.GLP-1 在神经元活动和神经退行性变中的作用。
Vitam Horm. 2010;84:331-54. doi: 10.1016/B978-0-12-381517-0.00013-8.
8
Characterization of promoter elements regulating the expression of the human neurotensin/neuromedin N gene.调控人类神经降压素/神经肽 N 基因表达的启动子元件的特征。
J Biol Chem. 2011 Jan 7;286(1):542-54. doi: 10.1074/jbc.M110.145664. Epub 2010 Oct 28.
9
CREB signalling regulates early survival, neuronal gene expression and morphological development in adult subventricular zone neurogenesis.CREB 信号转导调节成年侧脑室下区神经发生中的早期存活、神经元基因表达和形态发育。
Mol Cell Neurosci. 2011 Jan;46(1):79-88. doi: 10.1016/j.mcn.2010.08.008. Epub 2010 Aug 27.
10
Functions for pro-opiomelanocortin-derived peptides in obesity and diabetes.阿黑皮素原衍生肽在肥胖和糖尿病中的作用。
Biochem J. 2010 May 27;428(3):305-24. doi: 10.1042/BJ20091957.
Zotero 插件