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扫描离子电导显微镜。

Scanning ion conductance microscopy.

机构信息

Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.

出版信息

Annu Rev Anal Chem (Palo Alto Calif). 2012;5:207-28. doi: 10.1146/annurev-anchem-062011-143203. Epub 2012 Apr 9.

Abstract

Scanning ion conductance microscopy (SICM) is a versatile type of scanning probe microscopy for studies in molecular biology and materials science. Recent advances in feedback and probe fabrication have greatly increased the resolution, stability, and speed of imaging. Noncontact imaging and the ability to deliver materials to localized areas have made SICM especially fruitful for studies of molecular biology, and many examples of such use have been reported. In this review, we highlight new developments in the operation of SICM and describe some of the most exciting recent studies from this growing field.

摘要

扫描离子电导显微镜(SICM)是一种用于分子生物学和材料科学研究的多功能扫描探针显微镜。反馈和探针制造方面的最新进展极大地提高了成像的分辨率、稳定性和速度。非接触成像和向局部区域输送材料的能力使 SICM 特别适合于分子生物学研究,并且已经报道了许多这样的应用实例。在这篇综述中,我们强调了 SICM 操作的新发展,并描述了这个不断发展的领域中一些最令人兴奋的最新研究。

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