Faculty of Life and Physical Sciences, The University of Western Australia, Crawley, Perth 6009, Australia.
J Hum Lact. 2012 May;28(2):145-52. doi: 10.1177/0890334411435414.
Despite the increased metabolic activity of the lactating breast, no studies have been carried out to determine mammary blood flow (MBF) parameters or the relationship between MBF and milk production in women. The aim of this study was to measure the MBF in the internal mammary artery (IMA) and lateral thoracic artery (LTA) of lactating women and determine if these were related to milk production.
Blood flow in the IMA and LTA was measured with color Doppler ultrasound in 55 lactating women. Twenty-four-hour milk production was determined with the test-weigh method.
IMA contributed the greater proportion of blood flow to the lactating breast (70%). MBF was highly variable between women but consistent between the left (126 L/24 h; interquartile range, 76-169) and right (110 L/24 h) breasts. No relationship between MBF and milk production was demonstrated. For 3 women, MBF was markedly reduced in 1 breast that was synthesizing almost no milk compared to the other that was producing a normal volume of milk.
Although no relationship between MBF and milk production was found, the substantial reduction in blood flow in the breasts of lactating women producing almost no milk suggests a threshold below which milk production is compromised.
Doppler ultrasound did not demonstrate a relationship between MBF and milk production in lactating women. Further investigation is required to fully understand the role of blood flow in milk synthesis.
尽管哺乳期乳房的代谢活动增加，但尚无研究确定哺乳期妇女的乳腺血流（MBF）参数或 MBF 与产奶量之间的关系。本研究旨在测量哺乳期妇女的内乳动脉（IMA）和外侧胸动脉（LTA）的 MBF，并确定其与产奶量是否相关。
使用彩色多普勒超声测量 55 名哺乳期妇女的 IMA 和 LTA 的血流。使用测试称重法确定 24 小时产奶量。
IMA 对哺乳期乳房的血流贡献更大（70%）。MBF 在女性之间差异很大，但左（126 L/24 h；四分位距，76-169）和右（110 L/24 h）乳房之间的 MBF 一致。未发现 MBF 与产奶量之间存在相关性。对于 3 名妇女，与另一只产奶量正常的乳房相比，一只乳房的 MBF 明显减少，而该乳房几乎没有合成乳汁。
尽管未发现 MBF 与产奶量之间存在相关性，但哺乳期妇女中几乎没有乳汁合成的乳房的血流量大量减少表明，产奶量受损的阈值较低。
多普勒超声未显示哺乳期妇女 MBF 与产奶量之间存在关系。需要进一步研究以充分了解血流在乳汁合成中的作用。
