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[基于瞳孔的青光眼性视神经病变诊断的现状]

[Current state of pupil-based diagnostics for glaucomatous optic neuropathy].

作者信息

Skorkovská K, Schiefer U, Wilhelm B, Wilhelm H

机构信息

Depatment für Augenheilkunde, Schleichstr. 12-16, 72076, Tübingen, Deutschland.

出版信息

Ophthalmologe. 2012 Apr;109(4):351-7. doi: 10.1007/s00347-012-2547-6.

Abstract

There are considerable differences between pupillary reactions to light in glaucoma patients and healthy subjects which can be identified by various techniques. These methods are based on the early asymmetry of the afferent conduction in the visual pathway, on the examination of the visual field by focal light stimuli or on visual stimuli in analogy with multifocal electrophysiological tests. Latest findings in pupillary research also suggest a possible use of the intrinsically photosensitive (melanopsin expressing) retinal ganglion cells in glaucoma diagnostics. The current results of pupillary experiments in glaucoma patients are encouraging for further research in this field because suitable objective screening methods for glaucoma are continually being sought.

摘要

青光眼患者与健康受试者的瞳孔对光反应存在显著差异,可通过多种技术识别。这些方法基于视觉通路中传入传导的早期不对称性、通过焦点光刺激检查视野或类似于多焦点电生理测试的视觉刺激。瞳孔研究的最新发现还表明,内在光敏(表达黑视蛋白)视网膜神经节细胞在青光眼诊断中可能有用。青光眼患者瞳孔实验的当前结果为该领域的进一步研究带来了鼓舞,因为一直在寻找适合青光眼的客观筛查方法。

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