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对于阴道后壁膨出的修复,金标准是什么:网片还是固有组织?

What is the gold standard for posterior vaginal wall prolapse repair: mesh or native tissue?

机构信息

Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological and Kidney Institute, Cleveland Clinic, OH 44195, USA.

出版信息

Curr Urol Rep. 2012 Jun;13(3):216-21. doi: 10.1007/s11934-012-0248-y.

DOI:10.1007/s11934-012-0248-y
PMID:22528115
Abstract

Reports in the literature of high recurrence rates after native tissue repair for pelvic organ prolapse led to the development of alternative techniques, such as those using synthetic mesh. Transvaginal mesh (TVM) delivery systems were implemented in search of better outcomes. Despite reported recurrence as low as 7.1 % after posterior colporrhaphy, mesh kits were developed to correct posterior compartment prolapse. There is a paucity of data to substantiate better results with TVM for rectocele repair. Three randomized controlled trials comparing native tissue repair to synthetic mesh reported posterior compartment outcomes and two of these failed to show a significant difference between groups. Complications of TVM placement are not insignificant and mesh extrusion was reported in up to 16.9 %. Based on currently available data, native tissue repairs have similar outcomes to synthetic mesh without the risks inherent in mesh use and remain the standard of care for the typical patient.

摘要

文献报道,盆腔器官脱垂患者经固有组织修复后复发率较高,这促使人们开发了替代技术,如使用合成网片。为了获得更好的效果,采用了经阴道网片(TVM)输送系统。尽管阴道后壁修补术的复发率低至 7.1%,但仍开发了网片套件来纠正后盆腔器官脱垂。TVM 修复直肠膨出的结果更好,但数据很少。三项比较固有组织修复与合成网片的随机对照试验报告了后盆腔器官脱垂的结果,其中两项试验未能显示组间有显著差异。TVM 放置的并发症并非微不足道,网片挤出的发生率高达 16.9%。基于现有数据,固有组织修复与合成网片的结果相似,且不存在网片使用固有的风险,因此仍然是典型患者的护理标准。

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引用本文的文献

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Clin Colon Rectal Surg. 2014 Dec;27(4):182-90. doi: 10.1055/s-0034-1394157.
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Clinical challenges in the management of vaginal prolapse.阴道脱垂管理中的临床挑战。
Int J Womens Health. 2014 Jan 16;6:83-94. doi: 10.2147/IJWH.S54845. eCollection 2014.

本文引用的文献

1
Development of de novo prolapse in untreated vaginal compartments after prolapse repair with and without mesh: a secondary analysis of a randomised controlled trial.经阴道修补术(有无网片)后未治疗阴道隔新发脱垂的发展:一项随机对照试验的二次分析。
BJOG. 2012 Feb;119(3):354-60. doi: 10.1111/j.1471-0528.2011.03231.x.
2
One-year objective and functional outcomes of a randomized clinical trial of vaginal mesh for prolapse.阴道网片治疗脱垂的随机临床试验的一年目标和功能结果。
Am J Obstet Gynecol. 2012 Jan;206(1):86.e1-9. doi: 10.1016/j.ajog.2011.08.003. Epub 2011 Aug 11.
3
Surgical intervention after transvaginal Prolift mesh repair: retrospective single-center study including 524 patients with 3 years' median follow-up.
经阴道 Prolift 网片修复术后的手术干预:回顾性单中心研究,纳入 524 例患者,中位随访时间 3 年。
Am J Obstet Gynecol. 2012 Jan;206(1):83.e1-7. doi: 10.1016/j.ajog.2011.07.040. Epub 2011 Jul 30.
4
Transvaginal mesh surgery for pelvic organ prolapse--Prolift+M: a prospective clinical trial.经阴道网片治疗盆腔器官脱垂——Prolift+M:一项前瞻性临床试验。
Int Urogynecol J. 2011 Nov;22(11):1405-11. doi: 10.1007/s00192-011-1482-4. Epub 2011 Jul 1.
5
Vaginal prolapse repair using the Prolift kit: a registry of 100 successive cases.经阴道 Prolift 套件修复阴道脱垂:100 例连续病例的注册研究。
Eur J Obstet Gynecol Reprod Biol. 2011 Sep;158(1):104-9. doi: 10.1016/j.ejogrb.2011.04.027. Epub 2011 Jun 1.
6
Reanalysis of a randomized trial of 3 techniques of anterior colporrhaphy using clinically relevant definitions of success.采用临床相关的成功定义对 3 种前阴道壁修补术的随机试验进行重新分析。
Am J Obstet Gynecol. 2011 Jul;205(1):69.e1-8. doi: 10.1016/j.ajog.2011.03.027. Epub 2011 Mar 22.
7
Trocar-guided mesh compared with conventional vaginal repair in recurrent prolapse: a randomized controlled trial.经 Trocar 引导的网片与传统阴道修复术治疗复发性脱垂的比较:一项随机对照试验。
Obstet Gynecol. 2011 Feb;117(2 Pt 1):242-250. doi: 10.1097/AOG.0b013e318203e6a5.
8
An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint terminology and classification of the complications related directly to the insertion of prostheses (meshes, implants, tapes) and grafts in female pelvic floor surgery.国际尿控协会(IUGA)/国际尿失禁协会(ICS)关于女性盆底手术中与假体(网片、植入物、带子)和移植物直接相关的并发症的联合术语和分类。
Neurourol Urodyn. 2011 Jan;30(1):2-12. doi: 10.1002/nau.21036.
9
Lifetime risk of undergoing surgery for pelvic organ prolapse.盆腔器官脱垂手术的终身风险。
Obstet Gynecol. 2010 Nov;116(5):1096-100. doi: 10.1097/AOG.0b013e3181f73729.
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Trocar-guided mesh repair of vaginal prolapse using partially absorbable mesh: 1 year outcomes.经 Trocar 引导的部分可吸收网片在阴道膨出修补术中的应用:1 年随访结果。
Am J Obstet Gynecol. 2011 Jan;204(1):74.e1-8. doi: 10.1016/j.ajog.2010.08.036. Epub 2010 Oct 20.