Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom.
Magn Reson Med. 2013 Feb;69(2):486-94. doi: 10.1002/mrm.24280. Epub 2012 Apr 23.
Respiratory motion remains the major impediment in a substantial amount of patients undergoing coronary magnetic resonance angiography. Motion correction in coronary magnetic resonance angiography is typically performed with a diaphragmatic 1D navigator (1Dnav) assuming a constant linear relationship between diaphragmatic and cardiac respiratory motion. In this work, a novel 2D navigator (2Dnav) is proposed, which prospectively corrects for translational motion in foot-head and left-right direction. First, 1Dnav- and 2Dnav-based motion correction are compared in 2D real time imaging experiments, by evaluating the residual respiratory motion in 10 healthy subjects as well as in a moving vessel phantom. Subsequently, 1Dnav and 2Dnav corrected high-resolution 3D coronary MR angiograms were acquired, and both objective and subjective image quality were assessed. For a gating window of 10 mm, 1Dnav and 2Dnav performed equally well; however, without any respiratory gating, the 1Dnav had a lower visual score for all coronary arteries compared with 10 mm gating, whereas the 2Dnav without gating performed similar to 1Dnav with 10 mm gating.
呼吸运动仍然是大量接受冠状动脉磁共振血管造影的患者的主要障碍。冠状动脉磁共振血管造影中的运动校正通常使用膈肌 1D 导航仪(1Dnav)进行,假设膈肌和心脏呼吸运动之间存在恒定的线性关系。在这项工作中,提出了一种新颖的 2D 导航仪(2Dnav),它可以前瞻性地校正足部到头部和左右方向的平移运动。首先,通过评估 10 名健康受试者和运动血管模拟体中的残留呼吸运动,在 2D 实时成像实验中比较了基于 1Dnav 和 2Dnav 的运动校正。随后,获得了高分辨率的 3D 冠状动脉 MR 血管造影,并评估了客观和主观的图像质量。对于 10mm 的门控窗,1Dnav 和 2Dnav 的性能相当;然而,在没有任何呼吸门控的情况下,与 10mm 门控相比,所有冠状动脉的 1Dnav 视觉评分都较低,而无门控的 2Dnav 的表现与 10mm 门控的 1Dnav 相似。