Jain Arpita, Mendiratta Vibhu, Chander Ram
Department of Dermatology and STD, Lady Hardinge Medical College and Assoc. Sucheta Kriplani Hospital and Kalawati Saran Childrens Hospital, Delhi, India.
Indian J Sex Transm Dis AIDS. 2012 Jan;33(1):32-4. doi: 10.4103/0253-7184.93814.
Prevalence of sexually transmitted infection shows regional variations. Though a rising trend of prevalence of viral STI s has been observed, syphilis still continues to remain a commonly diagnosed STI.
To study the current status of acquired syphilis in a tertiary care hospital.
Retrospective analysis of all the cases of acquired syphilis registered in our hospital from 2005 to 2009 was done. Complete epidemiological, clinical, and investigational data were recorded and assessed.
Total of 570 cases attended the STI clinic from year 2005 to 2009. 42 (7.36%) cases were diagnosed as syphilis. There were 32 (74%) males and 11 (26%) were females. 25 (60%) were married. Only two patients were less than 15 years of age. Primary syphilis was diagnosed in 21 (50%), secondary in 10 (24%), and latent in 11 (26%) cases. Two (9.5%) of primary syphilis showed multiple chancre. Concomitant primary chancre and lesions of secondary syphilis were seen in 2 (20%) patients. Secondary syphilis presented as condyloma lata (50%), maculo-papular rash (40%), and lues maligna in one patient who was HIV positive. Mixed infection was diagnosed in eight patients of which herpes genitalis was the commonest. Two patients were serologically positive for HIV.
Incidence of syphilis had shown a constant trend over last 5 years. In lieu of change in trends of sexual practices, condyloma was the commonest presentation of secondary syphilis. Pustular syphilis was observed in association with HIV and could be a marker of the immune-deficient state.
性传播感染的患病率存在地区差异。尽管已观察到病毒性性传播感染的患病率呈上升趋势，但梅毒仍然是常见的确诊性传播感染。
研究一家三级医疗机构中后天梅毒的现状。
对2005年至2009年在我院登记的所有后天梅毒病例进行回顾性分析。记录并评估完整的流行病学、临床和检查数据。
2005年至2009年共有570例患者到性传播感染门诊就诊。其中42例（7.36%）被诊断为梅毒。男性32例（74%），女性11例（26%）。25例（60%）已婚。只有2例患者年龄小于15岁。一期梅毒诊断21例（50%），二期10例（24%），潜伏梅毒11例（26%）。2例一期梅毒（9.5%）表现为多发溃疡。2例患者（20%）同时出现一期溃疡和二期梅毒损害。二期梅毒表现为扁平湿疣（50%）、斑丘疹（40%），1例HIV阳性患者表现为恶性梅毒。8例患者诊断为混合感染，其中生殖器疱疹最为常见。2例患者HIV血清学阳性。
梅毒发病率在过去5年呈稳定趋势。鉴于性行为趋势的变化，扁平湿疣是二期梅毒最常见的表现。脓疱性梅毒与HIV感染相关，可能是免疫缺陷状态的一个标志。
