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中国内镜下切除术的现状。

Current status of endoscopic resection in China.

机构信息

Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.

出版信息

Dig Endosc. 2012 May;24 Suppl 1:166-71. doi: 10.1111/j.1443-1661.2012.01268.x.

DOI:10.1111/j.1443-1661.2012.01268.x
PMID:22533775
Abstract

The early diagnosis of early gastrointestinal (GI) diseases is becoming easier than ever before, due to the rapid development of all kinds of endoscopic techniques, including chromoendoscopy, narrowband imaging, magnifying endoscopy, confocal microscopy and autofluorescence imaging. Endoscopic resection is gradually becoming the optimal choice, which is significantly less invasive than conventional surgical interventions. In China, endoscopic resection techniques have been developed very quickly after several pioneers learned from Japanese gastroenterologists. Endoscopic submucosal dissection (ESD) has achieved remarkable initial outcomes, however, large-scale, multicenter, retrospective studies of the long-term follow up of ESD outcomes in China are still lacking. New endoscopic interventions are also being developed from the ESD technique, namely, endoscopic full-thickness resection of gastric submucosal tumors, peroral endoscopic myotomy and submucosal tunneling endoscopic resection techniques. Here, we discuss the current status of endoscopic resection in China and several problems: (i) the lack of guideline or consensus from academic society; (ii) approximately half of the ESD are performed on benign submucosal tumors, so the diagnosis of mucosal cancers needs to be increased; (iii) the standard technique used, results, management of complications and follow-up should be standardized; and (iv) the minimum training requirements, the step-by-step approach should also need to be standardized.

摘要

由于各种内镜技术的快速发展,包括色素内镜、窄带成像、放大内镜、共聚焦显微镜和自发荧光成像,早期胃肠道(GI)疾病的早期诊断变得比以往任何时候都更容易。内镜切除逐渐成为最佳选择,其创伤性明显小于传统的手术干预。在中国,几位先驱者向日本胃肠病学家学习后,内镜切除技术发展得非常迅速。内镜黏膜下剥离术(ESD)已取得显著的初步成果,但中国仍缺乏对 ESD 结果的长期随访的大规模、多中心、回顾性研究。还从 ESD 技术发展出新的内镜干预措施,即内镜胃黏膜下固有肌层肿瘤全层切除术、经口内镜肌切开术和黏膜下隧道内镜切除术。在这里,我们讨论中国内镜切除的现状和几个问题:(i)学术学会缺乏指南或共识;(ii)大约一半的 ESD 用于良性黏膜下肿瘤,因此需要增加黏膜癌的诊断;(iii)应标准化使用的标准技术、结果、并发症的处理和随访;以及(iv)还需要标准化最低培训要求和逐步方法。

相似文献

1
Current status of endoscopic resection in China.中国内镜下切除术的现状。
Dig Endosc. 2012 May;24 Suppl 1:166-71. doi: 10.1111/j.1443-1661.2012.01268.x.
2
State of the art on endoscopic mucosal resection and endoscopic submucosal dissection.内镜黏膜切除术和内镜黏膜下剥离术的技术现状
Gastrointest Endosc Clin N Am. 2007 Jul;17(3):441-69, v. doi: 10.1016/j.giec.2007.05.012.
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Endoscopic resection for early gastric cancer: current status in Korea.内镜下切除术治疗早期胃癌:韩国现状。
Dig Endosc. 2012 May;24 Suppl 1:159-65. doi: 10.1111/j.1443-1661.2012.01275.x.
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Successful outcomes of a novel endoscopic treatment for GI tumors: endoscopic submucosal dissection with a mixture of high-molecular-weight hyaluronic acid, glycerin, and sugar.一种新型内镜治疗胃肠道肿瘤的成功结果:使用高分子量透明质酸、甘油和糖的混合物进行内镜黏膜下剥离术。
Gastrointest Endosc. 2006 Feb;63(2):243-9. doi: 10.1016/j.gie.2005.08.002.
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Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) in 2011, a Western perspective.2011 年的内镜下黏膜切除术(EMR)和内镜黏膜下剥离术(ESD):西方视角。
Clin Res Hepatol Gastroenterol. 2011 Apr;35(4):288-94. doi: 10.1016/j.clinre.2011.02.006. Epub 2011 Mar 31.
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Current practice with endoscopic submucosal dissection in Europe: position statement from a panel of experts.欧洲内镜黏膜下剥离术的现状:专家组立场声明。
Endoscopy. 2010 Oct;42(10):853-8. doi: 10.1055/s-0030-1255563. Epub 2010 Jul 9.
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Endoscopic submucosal dissection in a European setting. A multi-institutional report of a technique in development.内镜黏膜下剥离术在欧洲的应用。一种技术发展的多机构报告。
Endoscopy. 2011 Aug;43(8):664-70. doi: 10.1055/s-0030-1256413. Epub 2011 May 27.
8
Technology insight: endoscopic submucosal dissection of gastrointestinal neoplasms.技术洞察:胃肠道肿瘤的内镜黏膜下剥离术
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Endoscopic submucosal dissection of early cancers, flat adenomas, and submucosal tumors in the gastrointestinal tract.胃肠道早期癌症、扁平腺瘤及黏膜下肿瘤的内镜黏膜下剥离术。
Clin Gastroenterol Hepatol. 2009 Feb;7(2):149-55. doi: 10.1016/j.cgh.2008.09.005. Epub 2008 Sep 20.
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Expanding indications for ESD: submucosal disease (SMT/carcinoid tumors).内镜黏膜下剥离术(ESD)的适应证扩展:黏膜下疾病(黏膜下肿瘤/类癌肿瘤)。
Gastrointest Endosc Clin N Am. 2014 Apr;24(2):169-81. doi: 10.1016/j.giec.2013.11.006. Epub 2014 Jan 25.

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The Comparison between Endoscopic Submucosal Dissection and Surgery in Gastric Cancer: A Systematic Review and Meta-Analysis.内镜下黏膜下剥离术与手术治疗胃癌的比较:一项系统评价和荟萃分析
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Impact of formal training in endoscopic submucosal dissection for early gastrointestinal cancer: A systematic review and a meta-analysis.早期胃肠道癌内镜黏膜下剥离术正规培训的影响:一项系统评价和荟萃分析。
World J Gastrointest Endosc. 2015 Apr 16;7(4):417-28. doi: 10.4253/wjge.v7.i4.417.
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New progress in endoscopic treatment of esophageal diseases.食管疾病内镜治疗的新进展。
World J Gastroenterol. 2013 Nov 7;19(41):6962-8. doi: 10.3748/wjg.v19.i41.6962.