Juul Jakob Søgaard, Larsen Thomas, Marcussen Niels, Pedersen Erling Bjerregaard
Medicinsk Afdeling, Medicinsk Forskning, Regionshospitalet Holstebro, Denmark.
Ugeskr Laeger. 2012 Apr 23;174(17):1159-60.
A 64 year-old woman with acute renal failure and cast nephropathy due to excessive production of lambda free light chains received chemotherapy (using bortezomib and dexamethason) and haemodialysis with a high cut off-filter. The concentration of free light chains was markedly reduced after a fortnight. Nine months after admission, the patient's kidney function had improved and dialysis was stopped. Three months later, she got an autologous stem cell transplantation. One year later, estimated glomerular filtration rate was 25 ml/min, and the production of free light chains was under control.
一名64岁女性因λ游离轻链产生过多导致急性肾衰竭和管型肾病，接受了化疗（使用硼替佐米和地塞米松）以及高通量血液透析。两周后游离轻链浓度显著降低。入院九个月后，患者肾功能改善，停止透析。三个月后，她接受了自体干细胞移植。一年后，估计肾小球滤过率为25毫升/分钟，游离轻链产生得到控制。
