Ribeiro J M, Ruiz A, Sillero M A, Sillero A
Departamento de Bioquímica, C.S.I.C., Facultad de Medicina, Universidad Autónoma de Madrid, Spain.
Clin Chim Acta. 1990 Oct 15;190(3):189-97. doi: 10.1016/0009-8981(90)90173-p.
Isoelectric point values have been determined from a theoretical standpoint for alpha, beta, gamma and delta human abnormal subunits bearing elimination or addition of 1-2 different aminoacids with acid-base residues. The charge distribution, in relation to pH values, of the four types of subunits are also reported. These values may be of interest both to predict the electrophoretic behaviour and to characterize human abnormal hemoglobins.
从理论角度确定了α、β、γ和δ人类异常亚基的等电点值，这些亚基带有1 - 2个不同氨基酸的去除或添加，且带有酸碱残基。还报道了这四种亚基相对于pH值的电荷分布情况。这些值对于预测电泳行为和表征人类异常血红蛋白可能都具有重要意义。
