Portelli Monique S, Tenni Brigitte, Kounnavong Sengchanh, Chanthivilay Phetsavanh
University of Melbourne, Melbourne, Victoria, Australia
Nossal Institute for Global Health, Melbourne, Victoria, Australia.
Asia Pac J Public Health. 2015 Mar;27(2):NP778-88. doi: 10.1177/1010539512442082. Epub 2012 Apr 24.
Adherence to antiretroviral therapy (ART) is essential to its effectiveness and avoidance of the development of drug-resistant HIV strains. Many studies have been undertaken on factors affecting adherence to ART; however, there is little information about Laos. Hence, this qualitative study examines barriers to and facilitators of adherence specific to this context. In-depth interviews and focus group discussions were undertaken with 43 people living with HIV (PLHIV) currently on ART across 2 hospitals in Laos: Setthathirath hospital in the capital Vientiane and Savannakhet Province hospital. Interviews were based on semistructured question guides and were undertaken in Lao, translated into English and audio-recorded for later analysis. Major barriers to adherence reported by participants included transport costs, distance to the hospital, and stigma and discrimination. Key facilitators discussed were the perceived benefits of medication, social support, and the acceptance of HIV status.
坚持抗逆转录病毒疗法（ART）对于其有效性以及避免耐药性艾滋病毒株的产生至关重要。关于影响ART依从性的因素已开展了许多研究；然而，关于老挝的相关信息却很少。因此，这项定性研究考察了这一背景下ART依从性的障碍和促进因素。对老挝两家医院（首都万象的Setthathirath医院和沙湾拿吉省医院）正在接受ART治疗的43名艾滋病毒感染者（PLHIV）进行了深入访谈和焦点小组讨论。访谈基于半结构化问题指南，用老挝语进行，翻译成英语并录音以便后续分析。参与者报告的主要依从障碍包括交通成本、到医院的距离以及耻辱和歧视。讨论的关键促进因素是药物治疗的感知益处、社会支持以及对艾滋病毒感染状况的接受。
