Department of Psychosis Studies, Institute of Psychiatry, King's College, DeCrespigny Park, London SE5 8AF, UK.
Schizophr Bull. 2012 Jun;38(4):695-703. doi: 10.1093/schbul/sbs066. Epub 2012 Apr 25.
Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.
尽管神经影像学研究已经进行了二十多年，但目前仍缺乏充分的证据来全面理解听觉幻觉（AH）的神经生物学基础。然而，通过对 AH 患者的影像学研究，我们已经取得了一些进展，这些研究一致报告了言语和语言、感觉和非感觉区域的结构和功能的改变。本报告提供了听觉幻觉神经影像学研究的最新进展，特别强调了最近的解剖学、生理学和神经化学成像研究。具体来说，我们提供了（1）对精神分裂症和非精神分裂症幻听者研究结果的综述，（2）对阻碍研究进展的关键问题的讨论，以及（3）对未来研究的实用建议。
