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本文引用的文献

1
Comparative analysis of algorithms for whole-genome assembly of pyrosequencing data.比较分析焦磷酸测序数据全基因组组装算法。
Brief Bioinform. 2012 May;13(3):269-80. doi: 10.1093/bib/bbr063. Epub 2011 Oct 21.
2
Eukaryotic gene prediction using GeneMark.hmm-E and GeneMark-ES.使用GeneMark.hmm-E和GeneMark-ES进行真核基因预测。
Curr Protoc Bioinformatics. 2011 Sep;Chapter 4:4.6.1-4.6.10. doi: 10.1002/0471250953.bi0406s35.
3
Whole-genome sequencing reveals distinct mutational patterns in closely related laboratory and naturally propagated Francisella tularensis strains.全基因组测序揭示了密切相关的实验室和自然传播的土拉弗朗西斯菌菌株中独特的突变模式。
PLoS One. 2010 Jul 19;5(7):e11556. doi: 10.1371/journal.pone.0011556.
4
Large direct repeats flank genomic rearrangements between a new clinical isolate of Francisella tularensis subsp. tularensis A1 and Schu S4.大型直接重复序列侧翼基因组重排在一株新型弗朗西斯菌亚种 tularensis A1 临床分离株和 Schu S4 之间。
PLoS One. 2010 Feb 3;5(2):e9007. doi: 10.1371/journal.pone.0009007.
5
Whole genome single nucleotide polymorphism based phylogeny of Francisella tularensis and its application to the development of a strain typing assay.基于全基因组单核苷酸多态性的土拉弗朗西斯菌系统发育及其在菌株分型检测方法开发中的应用。
BMC Microbiol. 2009 Oct 7;9:213. doi: 10.1186/1471-2180-9-213.
6
Complete genome sequence of Francisella tularensis subspecies holarctica FTNF002-00.弗朗西斯菌亚种 holarctica FTNF002-00 的全基因组序列。
PLoS One. 2009 Sep 16;4(9):e7041. doi: 10.1371/journal.pone.0007041.
7
Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies.属于低毒力和高毒力亚种的土拉弗朗西斯菌菌株的比较基因组特征分析。
PLoS Pathog. 2009 May;5(5):e1000459. doi: 10.1371/journal.ppat.1000459. Epub 2009 May 29.
8
Identification of Francisella tularensis subsp. tularensis A1 and A2 infections by real-time polymerase chain reaction.通过实时聚合酶链反应鉴定土拉弗朗西斯菌土拉亚种A1和A2感染
Diagn Microbiol Infect Dis. 2009 May;64(1):6-12. doi: 10.1016/j.diagmicrobio.2009.01.006. Epub 2009 Feb 18.
9
The metagenomics RAST server - a public resource for the automatic phylogenetic and functional analysis of metagenomes.宏基因组学RAST服务器——用于宏基因组自动系统发育和功能分析的公共资源。
BMC Bioinformatics. 2008 Sep 19;9:386. doi: 10.1186/1471-2105-9-386.
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Using 454 technology for long-PCR based sequencing of the complete mitochondrial genome from single Haemonchus contortus (Nematoda).利用454技术对单个捻转血矛线虫（线虫纲）的线粒体基因组进行基于长PCR的测序。
BMC Genomics. 2008 Jan 11;9:11. doi: 10.1186/1471-2164-9-11.

弗氏志贺菌毒力 A1 型菌株与其减毒 O 抗原突变株的基因组比较。

Genomic comparison between a virulent type A1 strain of Francisella tularensis and its attenuated O-antigen mutant.

机构信息

Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.

出版信息

J Bacteriol. 2012 May;194(10):2775-6. doi: 10.1128/JB.00152-12.

DOI:10.1128/JB.00152-12
PMID:22535949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3347185/
Abstract

We report the complete genome sequences of TI0902, a highly virulent type A1 strain, and TIGB03, a related, attenuated chemical mutant strain. Compared to the wild type, the mutant strain had 45 point mutations and a 75.9-kb duplicated region that had not been previously observed in Francisella species.

摘要

我们报告了 TI0902（一种高毒力 A1 型菌株）和 TIGB03（一种相关的、减毒化学突变菌株）的完整基因组序列。与野生型相比，突变株有 45 个点突变和一个 75.9kb 的重复区域，这在弗朗西斯菌属中以前没有观察到过。