Datta S, Zhuravlev B, Shamayov N, Sharma K N, Sudakov K V
Anokhin Institute of Normal Physiology, Moscow, USSR.
Indian J Physiol Pharmacol. 1990 Apr;34(2):115-9.
In mobile unanaesthetised adult rabbits, spontaneous single unit activities of CA3 neurons of Hippocampus showed a specific change in firing pattern in response to conditioned stimuli (CS+). This pattern could be correlated with changes in the general behaviour of these animals. Major deafferntation of the CA3 region did not alter the conditioned response, though neuronal firing pattern and behavioural response changed to that of the pre-conditioned state after antidromic stimulation of CA3 region through fimbria. The importance of CA3 region in memory retention process has been indicated in these experiments.
在未麻醉的成年活动家兔中，海马CA3神经元的自发单单位活动在对条件刺激（CS+）做出反应时，放电模式呈现出特定变化。这种模式可能与这些动物的一般行为变化相关。虽然通过海马伞对CA3区进行逆向刺激后，神经元放电模式和行为反应恢复到预处理前的状态，但CA3区的主要传入纤维切断并未改变条件反应。这些实验表明了CA3区在记忆保持过程中的重要性。
