Freud A, Canfi A, Sod-Moriah U A, Chayoth R
Department of Radiochemistry, Nuclear Research Center-Negev, Beer Sheva, Israel.
Isr J Med Sci. 1990 Nov;26(11):611-5.
The reproductive capacity of mature rats at the age of 8 days was studied following neonatal exposure to 0.06 Gy dose of gamma-radiation. Decreased litter size and reduced body weight of the pups on weaning day, but not at parturition, were observed in female rats. The reduced litter size was not associated with impaired ovulation, impaired uterine implantation or mortality in utero, but resulted from increased death rate or at near parturition. Of the neonatally irradiated males 29% were found to be sterile and had degenerated or necrotic testes. The testicular damage and the reduced growth rate of the offspring of the irradiated females demonstrate the extreme sensitivity of the immature reproductive system to ionizing radiation, even at very low doses.
研究了新生大鼠在出生后接受0.06 Gy剂量的γ射线照射后，8日龄成熟大鼠的生殖能力。在雌性大鼠中观察到，断奶时幼崽的窝仔数减少且体重减轻，但分娩时未出现这种情况。窝仔数减少与排卵受损、子宫着床受损或子宫内死亡无关，而是由于临近分娩时死亡率增加所致。在新生期接受照射的雄性大鼠中，发现29%不育，睾丸出现退化或坏死。受照射雌性大鼠后代的睾丸损伤和生长速率降低表明，即使在非常低的剂量下，未成熟的生殖系统对电离辐射也极其敏感。
