Gui Rong, Nie Xin-Min, Wen Xian-Hui, Liu Jing
Department of Transfusion, Central South University, Changsha, Hunan Province, China.
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Apr;20(2):381-5.
This study was purposed to analyze the efficiency of platelet transfusion and to explore factors influencing platelet transfusion efficiency. 727 times of platelets transfusion in 254 patients in The Third Xiangya Hospital from September 2010 to May 2011 were analyzed retrospectively. Moreover, according to symptoms, times of platelet transfusion, blood types and splenomegaly, the corrected count of increment (CCI) and percentage of platelet recovery (PPR) were calculated for evaluation of platelet transfusion efficiency. The results showed that there were 456 effective transfusions out of 727 transfusions (62.72). Among them, the therapeutic effect of platelet transfusion for patients with acute blood loss anemia and chronic systemic diseases was relatively obvious, specially for chronic renal disease, the effective efficiency of them was 94.12. The patients with splenomegaly showed a significant impact on platelet transfusion efficiency (41.07). Analysis found that the frequency of platelet transfusion negatively correlated with transfusion efficiency. It is concluded that the transfusion frequency and splenomegaly are factors influencing the transfusion efficiency.
本研究旨在分析血小板输注的效率，并探讨影响血小板输注效率的因素。回顾性分析了2010年9月至2011年5月在中南大学湘雅三医院254例患者的727次血小板输注情况。此外，根据症状、血小板输注次数、血型和脾肿大情况，计算校正后血小板增加值（CCI）和血小板回收率（PPR），以评估血小板输注效率。结果显示，727次输注中有456次有效输注（62.72%）。其中，血小板输注对急性失血性贫血和慢性全身性疾病患者的治疗效果较为明显，特别是对慢性肾病患者，其有效率为94.12%。脾肿大患者对血小板输注效率有显著影响（41.07%）。分析发现，血小板输注频率与输注效率呈负相关。结论是，输注频率和脾肿大是影响输注效率的因素。
