Internal Medicine and Pathology Services Division, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia.
J Infect Public Health. 2012 Apr;5(2):140-4. doi: 10.1016/j.jiph.2011.11.006. Epub 2012 Feb 3.
Lymphadenopathy is a common medical problem. A lymph node biopsy may be necessary for definitive diagnosis in selected cases.
The study group included a retrospective, hospital-based series of patients who had a cervical lymph node biopsy at the Saudi Aramco Medical Services organization between 1997 and 2008.
During the study period, there were a total of 452 cervical lymph node biopsies. Biopsies were performed on 122 (27%) children ≤18 years and 81 (18%) patients >60 years. The most common histopathological diagnosis was reactive disease (52.2%, n=236), which was followed by granulomatous disease (15.5%, n=70). We detected carcinoma in 14.6% of the patients (n=66), Hodgkin's lymphoma in 8.8% (n=40) and non-Hodgkin's disease in 8.8% (n=40). Malignancy was more common in adults than children (19.5% vs. 1.6%, respectively and reactive disease was more common in children than adults (65.3% vs. 47.3%, respectively). Metastatic disease was more likely in the older age group (17.7% vs. 0%), Hodgkin's disease was found in 12.5% of the adolescents, and non-Hodgkin's disease was present in 10.3% of the adults and elderly.
The most common histopathological findings for cervical lymph node biopsies in eastern Saudi Arabia were reactive disease and granulomatous disease.
淋巴结病是一种常见的医学问题。在某些特定情况下，淋巴结活检可能是明确诊断所必需的。
研究组包括 1997 年至 2008 年期间在沙特阿美医疗服务组织进行的一项回顾性基于医院的患者颈淋巴结活检系列。
在研究期间，共进行了 452 例颈淋巴结活检。122 例（27%）≤18 岁的儿童和 81 例（18%）>60 岁的患者进行了活检。最常见的组织病理学诊断是反应性疾病（52.2%，n=236），其次是肉芽肿性疾病（15.5%，n=70）。我们在 14.6%的患者（n=66）中检测到癌，8.8%（n=40）为霍奇金淋巴瘤，8.8%（n=40）为非霍奇金淋巴瘤。恶性肿瘤在成年患者中比儿童患者更常见（分别为 19.5%和 1.6%），反应性疾病在儿童患者中比成年患者更常见（分别为 65.3%和 47.3%）。转移疾病在老年组中更常见（17.7%对 0%），霍奇金病在 12.5%的青少年中发现，非霍奇金病在 10.3%的成年和老年患者中存在。
在沙特阿拉伯东部，颈淋巴结活检最常见的组织病理学发现是反应性疾病和肉芽肿性疾病。
