Khajanchi Monty, Bambarkar Supriya, Gadgil Anita, Roy Nobhojit
Seth G.S. Medical College and KEM Hospital, Mumbai, 400012 India.
Tata Memorial Hospital, Mumbai, 400012 India.
Indian J Otolaryngol Head Neck Surg. 2016 Sep;68(3):345-51. doi: 10.1007/s12070-015-0832-9. Epub 2015 Feb 4.
The aim of this study is to estimate the incidence of cervical node tuberculosis (TB) in an urban middle class population and to describe an effective protocol for management of cervical lymphadenopathy. The present study is a prospective observational study conducted over two years (2007-2009) in a community hospital in Mumbai, India. All adults (age ≥14 years) presenting with cervical lymphadenopathy, not resolving were included and their details of history and examination were noted. All patients were subjected to fine needle aspiration cytology (FNAC) and biopsy was done selectively as indicated. The response at 1, 3 and 6 months of starting anti tuberculous treatment (ATT) were noted. A total of 191 patients were included in this study. The mean age was 41 years and male to female ratio was 1:1.1 in patients with cervical lymphadenopathy. A history of contact with a patient of TB was the most significantly associated history seen in patients diagnosed to have TB of cervical nodes (p < 0.001). TB (38.7%) followed by reactive nodes (37.6%) were the most common etiologies. A 90.6% response rate was seen in patients taking 6 months ATT for cervical node TB. The incidence of adult (≥14 years) cervical node TB was 52/100,000 people in an urban middle class community in Mumbai. A single swelling in the neck without other associated symptoms or signs was the commonest mode of presentation of TB of the neck nodes. A history of contact with TB, demonstrated an association with the final diagnosis of tuberculous lymphadenopathy.
本研究的目的是估计城市中产阶级人群中颈淋巴结结核(TB)的发病率,并描述一种有效的颈淋巴结病管理方案。本研究是一项前瞻性观察性研究,于2007年至2009年在印度孟买的一家社区医院进行了两年。所有出现颈淋巴结病且未缓解的成年人(年龄≥14岁)均被纳入研究,并记录其病史和检查细节。所有患者均接受细针穿刺细胞学检查(FNAC),并根据需要选择性地进行活检。记录开始抗结核治疗(ATT)后1、3和6个月时的反应。本研究共纳入191例患者。颈淋巴结病患者的平均年龄为41岁,男女比例为1:1.1。在被诊断为颈淋巴结结核的患者中,与结核病患者接触史是最显著相关的病史(p<0.001)。结核病(38.7%)其次是反应性淋巴结(37.6%)是最常见的病因。接受6个月ATT治疗的颈淋巴结结核患者的有效率为90.6%。在孟买的一个城市中产阶级社区,成人(≥14岁)颈淋巴结结核的发病率为52/100,000人。颈部单个肿胀且无其他相关症状或体征是颈淋巴结结核最常见的表现方式。与结核病接触史与结核性淋巴结病的最终诊断相关。