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儿童经皮内镜胃造口术的并发症:意大利多中心观察研究结果。

Complications of percutaneous endoscopic gastrostomy in children: results of an Italian multicenter observational study.

机构信息

Pediatric Surgery Unit, University of Padova, Padua, Italy.

出版信息

Dig Liver Dis. 2012 Aug;44(8):655-9. doi: 10.1016/j.dld.2012.03.017. Epub 2012 Apr 25.

DOI:10.1016/j.dld.2012.03.017
PMID:22541388
Abstract

BACKGROUND

Percutaneous endoscopic gastrostomy is the preferred way to achieve an artificial feeding route for patients requiring long-term enteral nutrition. Although the procedure is well-standardized, it carries early and late complications.

AIM

To establish the mortality and morbidity of this technique in a large cohort of children.

METHODS

A multi-centre prospective clinical data collection from children undergoing percutaneous endoscopic gastrostomy tube implantation has been conducted from January 2004 to December 2007. Previous abdominal surgery was the only exclusion criterion. Follow-up visits were carried out at 1, 3, 6, 12, and 24 months after the procedure.

RESULTS

239 children (males, 55.2%; mean age 6.05±6.1years) were enrolled from nine tertiary Italian centres. Major complications occurred in 8 patients (3.3%). The cumulative incidence of complications was 47.7% at 24 months. The presence of thoraco-abdominal deformity was an independent predictor of complications at 12 months. No risk factors were identified in association to complications during the 1st tube replacement.

CONCLUSION

In children undergoing percutaneous endoscopic gastrostomy placement minor complications are common, while severe morbidities are rare. Accurate follow up is essential to recognize every complication, in particular when risk factors such as thoraco-abdominal deformity exist.

摘要

背景

经皮内镜胃造口术是需要长期肠内营养的患者实现人工喂养途径的首选方法。虽然该操作已经得到了很好的标准化,但仍存在早期和晚期并发症。

目的

在大量儿童队列中确定该技术的死亡率和发病率。

方法

从 2004 年 1 月至 2007 年 12 月,对接受经皮内镜胃造口管植入术的儿童进行了多中心前瞻性临床数据收集。既往腹部手术是唯一的排除标准。在手术后 1、3、6、12 和 24 个月进行随访。

结果

从 9 个意大利三级中心共纳入 239 名儿童(男性占 55.2%;平均年龄 6.05±6.1 岁)。8 名患者(3.3%)发生严重并发症。24 个月时并发症累积发生率为 47.7%。胸腹部畸形的存在是 12 个月时并发症的独立预测因素。在第 1 次更换胃管期间,未发现与并发症相关的危险因素。

结论

在接受经皮内镜胃造口术的儿童中,常见轻微并发症,而严重并发症罕见。准确的随访对于识别每一种并发症至关重要,特别是当存在胸腹部畸形等危险因素时。

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