Ghosal Nandita, Kumaran Sunitha P, Furtado Sunil V, Hegde Alangar S
Department of Pathology and transfusion Medicine, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India.
Clin Neuropathol. 2012 Sep-Oct;31(5):374-8. doi: 10.5414/NP300437.
We present 2 rare cases of mixed schwannoma with meningioma. The first case was sporadic, in a 38-year-old female in cervical spine (C₂). The second case was a 24-year-old female, associated with NF-2, involving bilateral cerebellopontine angle with extension into the left cavernous sinus, sellar region with erosion of the petrous ridge and multiple intradural extramedullary lesions in the spinal cord suggestive of neurofibromas. To date only 12 cases of such tumors are documented in the literature. To the best of our knowledge this is the first case of sporadic mixed schwannoma with meningioma in cervical spine (C₂).
我们报告2例罕见的混合性神经鞘瘤合并脑膜瘤病例。第一例为散发性,患者为一名38岁女性,病变位于颈椎(C₂)。第二例患者为一名24岁女性,与神经纤维瘤病2型(NF-2)相关,累及双侧桥小脑角并延伸至左侧海绵窦、鞍区,岩骨嵴受侵蚀,脊髓内有多个硬膜内髓外病变,提示为神经纤维瘤。迄今为止,文献中仅记载了12例此类肿瘤。据我们所知,这是首例颈椎(C₂)散发性混合性神经鞘瘤合并脑膜瘤病例。