Oviedo Angelica, Pang Dachling, Zovickian John, Smith Matthew
Department of Pathology, Kaiser Foundation Hospital, Oakland, CA 94611, USA.
Pediatr Dev Pathol. 2005 May-Jun;8(3):386-90. doi: 10.1007/s10024-005-0119-3. Epub 2005 Jul 14.
Clear cell meningioma (CCM) is a rare variant of meningioma. Only 17 cases have been previously reported in children. Although it has bland cytologic features, it has a higher rate of recurrence than does conventional meningioma. This variant has been reported in sites such as spinal/intradural (lumbar and thoracic), cerebellopontine angle, and supratentorial. The differential diagnosis of CCM includes microcystic meningioma, hemangioblastoma, and clear cell ependymoma. The characteristic histology and immunohistochemistry leads to the diagnosis. We present a case of a 7-year-old boy with a CCM of the cauda equina and a review of pediatric CCM.
透明细胞型脑膜瘤(CCM)是脑膜瘤的一种罕见变异型。此前仅有17例儿童病例报道。尽管其细胞形态学特征较为温和,但与传统脑膜瘤相比,其复发率更高。该变异型已在脊髓/硬膜内(腰段和胸段)、桥小脑角及幕上等部位有报道。CCM的鉴别诊断包括微囊性脑膜瘤、血管母细胞瘤及透明细胞型室管膜瘤。其特征性的组织学和免疫组化表现有助于诊断。我们报告一例7岁男孩马尾神经的CCM病例,并对儿童CCM进行综述。