Nanomedicine Laboratory, UCL School of Pharmacy, University College London, London, UK.
Arch Toxicol. 2012 Jul;86(7):1009-20. doi: 10.1007/s00204-012-0860-0. Epub 2012 May 1.
Nanomedicine is an emerging field that proposes the application of precisely engineered nanomaterials for the prevention, diagnosis and therapy of certain diseases, including neurological pathologies. Carbon nanotubes (CNT) are a new class of nanomaterials, which have been shown to be promising in different areas of nanomedicine. In this review, the application of CNT interfacing with the central nervous system (CNS) will be described, and representative examples of neuroprosthetic devices, such as neuronal implants and electrodes will be discussed. Furthermore, the possible application of CNT-based materials as regenerative matrices of neuronal tissue and as delivery systems for the therapy of CNS will be presented.
纳米医学是一个新兴的领域，它提出了将精确设计的纳米材料应用于某些疾病（包括神经病理学）的预防、诊断和治疗。碳纳米管（CNT）是一类新型的纳米材料，已被证明在纳米医学的不同领域具有广阔的应用前景。在这篇综述中，将描述 CNT 与中枢神经系统（CNS）相互作用的应用，并讨论神经修复装置的代表性实例，如神经元植入物和电极。此外，还将介绍 CNT 基材料作为神经元组织再生基质和作为 CNS 治疗的递药系统的可能应用。
