Laursen Emilie Lund, Rasmussen Birthe Krogh
Department of Neurology, Hillerød Hospital, Hillerød, Denmark.
Dan Med J. 2012 May;59(5):A4437.
Danish healthcare seeks to improve cancer survival through improved diagnostics, rapid treatment and increased focus on cancer prevention and early help-seeking. In neuro-oncology, this has resulted in the Integrated Brain Cancer Pathway (IBCP). The paper explores how the pathway works in the initial phase in a clinical setting with emphasis on pathway criteria.
All patients admitted during the first two-year period to a regional neurology department in Denmark and fulfilling the IBCP inclusion criteria were included. Data regarding onset symptoms, diagnosis and time for diagnostic work-up were obtained and supplemented by a retrospective review of patient records. Sensitivities, specificities and positive predictive values of the inclusion criteria were calculated with magnetic resonance imaging scan of the cerebrum as index of validity.
The strength of the pathway inclusion criteria was determined largely by the number of criteria fulfilled and by the type of predominant symptoms. The criteria identified the majority of patients with symptomatic brain malignancy and were also highly predictive of general structural brain lesions.
The introduction of the pathway is a major step forward in the efforts to optimize brain cancer patients' illness trajectory.
This study was funded by a grant from the Danish Ministry of Health and Interior Affairs 2009 and the Helen Rude Foundation and has been approved by the Danish Data Protection Agency.
not relevant.
丹麦医疗保健系统致力于通过改进诊断、加快治疗以及更加关注癌症预防和早期求助来提高癌症生存率。在神经肿瘤学领域，这催生了综合脑癌诊疗路径（IBCP）。本文探讨了该路径在临床环境初始阶段的运作方式，重点关注路径标准。
纳入了在丹麦某地区神经科头两年期间收治的所有符合IBCP纳入标准的患者。获取了有关起病症状、诊断及诊断检查时间的数据，并通过回顾患者病历进行补充。以大脑磁共振成像扫描作为有效性指标，计算纳入标准的敏感性、特异性和阳性预测值。
该路径纳入标准的力度很大程度上取决于满足标准的数量以及主要症状的类型。这些标准识别出了大多数有症状的脑恶性肿瘤患者，并且对一般脑结构性病变也具有很高的预测性。
该路径的引入是优化脑癌患者病程的努力中向前迈出的重要一步。
本研究由丹麦卫生和内政部2009年的一笔赠款以及海伦·鲁德基金会资助，并已获得丹麦数据保护局的批准。
不相关。
