Kirichenko L L, Lekokhmakher S S, Popunova A K, Smirnov V V, Narynskiĭ A K
Kardiologiia. 1990 Aug;30(8):10-4.
The paper presents the changes found in the lipid spectrum in 48, platelet aggregation in 23 and microcirculation in 35 patients with coronary heart disease after plasmapheresis. In patients with Functional Classes III and IV angina, repeated procedures of plasmapheresis were found to result in a clinical improvement of its course in 92% of the patients and in conversion to a lower functional class of angina in 71%. Massive plasmapheresis performed by the developed methods caused a significant improvement in the lipid spectrum, blood rheology, and microcirculation, which persisted for 1 to 6 months after plasmapheresis in relation to the type of hyperlipoproteinemia.
该论文介绍了48例冠心病患者血浆置换后血脂谱的变化、23例患者血小板聚集情况以及35例患者微循环的变化。在Ⅲ级和Ⅳ级心绞痛患者中，发现重复进行血浆置换可使92%的患者临床病程得到改善，71%的患者心绞痛功能分级降低。采用所开发方法进行的大规模血浆置换显著改善了血脂谱、血液流变学和微循环，根据高脂蛋白血症类型，这些改善在血浆置换后可持续1至6个月。
