Department of Endocrinology, KEM Hospital, Mumbai, India.
Gynecol Endocrinol. 2012 Jul;28(7):533-5. doi: 10.3109/09513590.2011.632789. Epub 2012 May 2.
Pregnancy occurs rarely in patients with Cushing syndrome (CS) due to hypercortisolism. So far, about 150 cases of CS in pregnancy have been reported in the literature. We describe a 22-year-old female who presented in pregnancy with clinical features of CS. She delivered at 34 weeks of gestation and baby had transient adrenal insufficiency in the neonatal period. Mother underwent transsphenoidal surgery 1 year postpartum and on follow up she is under remission. Neonatal hypoadrenalism should be anticipated in maternal CS.
由于皮质醇增多症,患有库欣综合征(CS)的患者很少怀孕。到目前为止,文献中已经报道了大约 150 例 CS 妊娠病例。我们描述了一名 22 岁女性,她在妊娠期间出现 CS 的临床特征。她在妊娠 34 周时分娩,婴儿在新生儿期有短暂的肾上腺功能不全。母亲在产后 1 年接受了经蝶窦手术,随访时她处于缓解状态。患有 CS 的产妇应预期新生儿肾上腺功能减退。