York Institute for Health Research, York University, Toronto, Ontario, Canada.
Maturitas. 2012 Jul;72(3):229-35. doi: 10.1016/j.maturitas.2012.03.017. Epub 2012 Apr 30.
This paper sheds light on the dynamic relationship between people's experiences of low income and the development of type 2 diabetes (T2DM) by moving beyond the static perspective provided by cross-sectional studies to a long-term approach informed by longitudinal analyses.
We analyzed data from the Canadian National Population Health Survey (NPHS) conducted by Statistics Canada from 1994 to 2007. The longitudinal sample is composed of 17,276 respondents (8046 males, 9230 females) 12 years of age or older. We further developed an algorithm to distinguish T2DM from other types of diabetes. Proportional hazard models with time-varying predictors were used to explore the dynamics of the relationship between low income and T2DM.
The results suggest that living in low income and experiencing persistent low income are significant precursors of developing T2DM. Being in low income in the previous cycle of T2DM onset was associated with 77% higher risk of T2DM (hazard ratio 1.77; 95% CI: 1.48-2.12). The association between low income and diabetes incidence remains significant after adjusting for age, sex, health behaviors, and psychological distress (hazard ratio 1.24; 95% CI: 1.02-1.52).
This study contributes to the under-developed research examining longitudinally the relationship between socioeconomic status and diabetes incidence. Employing this long-term approach, this study calls attention to the primary effect of socioeconomic position on diabetes incidence that cannot be explained entirely by behavioral factors. Findings draw attention to the need to address the role played in T2DM by the inequitable distribution of the social determinants of health.
本研究超越了横断面研究提供的静态视角,采用纵向分析提供的长期方法,揭示了人们低收入经历与 2 型糖尿病(T2DM)发展之间的动态关系。
我们分析了加拿大统计局(Statistics Canada)于 1994 年至 2007 年开展的加拿大全国人口健康调查(NPHS)的数据。纵向样本由 17276 名年龄在 12 岁及以上的受访者(男性 8046 名,女性 9230 名)组成。我们进一步开发了一种算法来区分 T2DM 和其他类型的糖尿病。使用具有时变预测因子的比例风险模型来探讨低收入与 T2DM 之间关系的动态变化。
研究结果表明,生活在低收入环境中和持续处于低收入状态是发生 T2DM 的重要前兆。在前一轮 T2DM 发病周期中处于低收入状态与 T2DM 风险增加 77%相关(风险比 1.77;95%CI:1.48-2.12)。在调整年龄、性别、健康行为和心理困扰因素后,低收入与糖尿病发病之间的关联仍然显著(风险比 1.24;95%CI:1.02-1.52)。
本研究丰富了关于社会经济地位与糖尿病发病之间纵向关系的研究。通过采用长期方法,本研究提请注意社会经济地位对糖尿病发病的主要影响,这一影响不能完全用行为因素来解释。研究结果提请注意需要解决健康社会决定因素的不平等分配在 T2DM 中所起的作用。