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加拿大的 2 型糖尿病:最弱势群体中的男性风险集中,但女性群体中呈反向社会梯度分布。

Type 2 diabetes in Canada: concentration of risk among most disadvantaged men but inverse social gradient across groups in women.

机构信息

Department of Medicine, McGill University, Montreal, QC, Canada.

出版信息

Diabet Med. 2010 May;27(5):522-31. doi: 10.1111/j.1464-5491.2010.02982.x.

DOI:10.1111/j.1464-5491.2010.02982.x
PMID:20536947
Abstract

AIMS

To assess sex-specific associations of educational and income levels with Type 2 diabetes mellitus.

METHODS

Logistic regression analyses (Canadian Community Health Survey, cross-sectional) adjusted for ethnicity, immigration, urban/rural, overweight/obesity, physical inactivity, smoking, chronic conditions and regular physician.

RESULTS

Compared to women with some post-secondary education, Type 2 diabetes was more likely in both high school graduates without post-secondary education [odds ratio (OR) 1.27, 95% confidence interval (CI) 1.07-1.51] and high school non-completers (OR 1.73, 95% CI 1.47-2.04); among men, definitive conclusions in high school graduates without post-secondary education could not be drawn (OR 0.93, 95% CI 0.78-1.12), but Type 2 diabetes was more likely in high school non-completers (OR 1.26, 95% CI 1.08-1.48). Compared to women with the highest income, Type 2 diabetes was three times more likely in the lowest income group (OR 2.90, 95% CI 2.25-3.73), 2.53 times more likely in the low middle income group (OR 2.53, 95% CI 1.98-3.24) and 55% more likely in the high middle income group (OR 1.55, 95% CI 1.20-2.01). Among men, Type 2 diabetes was approximately 40% more likely in both the lowest (OR 1.41, 95% CI 1.10-1.80) and low middle income groups (OR 1.39, 95% CI 1.12-1.71); definitive conclusions in the high middle income group could not be drawn (OR 1.05, 95% CI 0.87-1.28).

CONCLUSIONS

In women, Type 2 diabetes increased monotonically with lower educational and income levels; in men, Type 2 diabetes was concentrated in the least educated and least affluent. Our findings support the need for policies and practices that lower diabetes risk among the most disadvantaged women and men and moderately disadvantaged women.

摘要

目的

评估教育和收入水平与 2 型糖尿病之间的性别特异性关联。

方法

使用逻辑回归分析(加拿大社区健康调查,横断面)调整了种族、移民、城乡、超重/肥胖、身体活动不足、吸烟、慢性病和定期就诊医生等因素。

结果

与具有一定高等教育程度的女性相比,高中毕业后未接受高等教育的女性(比值比 [OR] 1.27,95%置信区间 [CI] 1.07-1.51)和高中未毕业的女性(OR 1.73,95% CI 1.47-2.04)患 2 型糖尿病的可能性更大;而在男性中,高中毕业后未接受高等教育的人群中,无法得出明确的结论(OR 0.93,95% CI 0.78-1.12),但高中未毕业的男性(OR 1.26,95% CI 1.08-1.48)患 2 型糖尿病的可能性更大。与收入最高的女性相比,收入最低组(OR 2.90,95% CI 2.25-3.73)患 2 型糖尿病的可能性是其三倍,中低收入组(OR 2.53,95% CI 1.98-3.24)的可能性是两倍五,中高收入组(OR 1.55,95% CI 1.20-2.01)的可能性增加 55%。在男性中,收入最低(OR 1.41,95% CI 1.10-1.80)和中低收入(OR 1.39,95% CI 1.12-1.71)组患 2 型糖尿病的可能性大约增加了 40%;而中高收入组则无法得出明确的结论(OR 1.05,95% CI 0.87-1.28)。

结论

在女性中,2 型糖尿病随着教育和收入水平的降低而呈单调递增;在男性中,2 型糖尿病集中在受教育程度最低和最贫困的人群中。我们的研究结果支持制定政策和实践的必要性,以降低最弱势群体中女性和男性以及处于中度不利地位的女性的糖尿病风险。

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