Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Nat Struct Mol Biol. 2012 May 3;19(5):467-9. doi: 10.1038/nsmb.2290.
Dyneins are the largest of the cytoskeletal motor proteins, and their mechanochemical behavior is complex. Recent high-resolution crystallographic structures have revealed new surprises regarding motor domain organization and new insights into how force and movement are achieved.
动力蛋白是细胞骨架中最大的马达蛋白,其机械化学行为非常复杂。最近的高分辨率晶体结构揭示了有关马达结构域组织的新惊喜,并深入了解了力和运动是如何产生的。