Virology Division, Laboratório Central de Saúde Pública de Pernambuco, Recife, PE, Brazil.
Braz J Infect Dis. 2012 Mar-Apr;16(2):157-63. doi: 10.1016/s1413-8670(12)70298-2.
The BED capture enzyme immunoassay test makes it possible to determine whether individuals were recently infected with HIV.
In this study, the overall HIV and recent infections prevalences were determined at five Voluntary Counseling and Testing (VCT) centers, in the Metropolitan Region of Recife, Northeastern of Brazil.
A cross-sectional study was conducted among users of five VCTs in the metropolitan region of Recife between July 2007 and April 2009. Out of the individuals who tested positive for HIV, 169 were analyzed to assess the prevalence of recent infection by means of the BED-CEIA (BED-Calypte®).
Out of 46,696 individuals tested 916 (1.96%) turned out positive for HIV infection The highest prevalence was in Recife (3.9%). The prevalence was higher among males (3.93%), and men who have sex with men (MSM) (12.4%). The frequency of recent infections among the 169 subjects evaluated was 23.7%. Recent infections were more common among individuals under 25 years of age. There was slight predominance of men and higher frequency of heterosexuals in both groups, but still a significant portion of MSM (33%). Subtype B predominated, followed by a high proportion of subtype F.
Recent infection occurs mainly among young individuals and heterosexuals, despite a significant proportion of recent infection among MSM. These results suggest that preventive actions aimed at the MSM community remains a challenge and efforts focusing this group should continue to be a priority.
BED 捕获酶免疫测定试验使得确定个体最近是否感染 HIV 成为可能。
本研究旨在确定巴西东北部累西腓大都市区五个自愿咨询检测 (VCT) 中心的 HIV 总流行率和近期感染流行率。
2007 年 7 月至 2009 年 4 月,在累西腓大都市区的五个 VCT 中心开展了一项横断面研究。对经 HIV 检测呈阳性的 169 名个体进行分析,以通过 BED-CEIA(BED-Calypte®)评估近期感染的流行率。
在 46696 名接受检测的个体中,有 916 名(1.96%)HIV 感染呈阳性。雷西腓(3.9%)的流行率最高。男性(3.93%)和男男性行为者(MSM)(12.4%)的流行率更高。在评估的 169 名个体中,最近感染的频率为 23.7%。最近的感染在 25 岁以下的个体中更为常见。男性略占优势,两个群体中的异性恋者比例较高,但仍有相当一部分 MSM(33%)。B 亚型占主导地位,其次是高比例的 F 亚型。
最近的感染主要发生在年轻个体和异性恋者中,尽管 MSM 中有相当一部分最近感染。这些结果表明,针对 MSM 群体的预防措施仍然是一个挑战,应继续将该群体作为重点。