Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, PR China.
Nanoscale. 2012 Jun 7;4(11):3501-6. doi: 10.1039/c2nr30310h. Epub 2012 May 2.
Copper sulfide (CuS) concave polyhedral superstructures (CPSs) have been successfully prepared in an ethanolic solution by a simple solvothermal reaction without the use of surfactants or templates. Two typical well defined, high symmetry CuS concave polyhedrons, forming a concave truncated cuboctahedron and icosahedron were prepared. The effect of the reaction time, temperature and different Cu ion and sulfur sources on the formation of CuS CPSs were investigated and a possible formation mechanism was proposed and discussed based on gas chromatography-mass spectrometry. More importantly, we found, for the first time, that the CuS CPSs exhibit intrinsic peroxidase-like activity, as they can quickly catalyze the oxidation of typical horseradish peroxidase (HRP) substrates, 3,3',5,5'-tetramethylbenzidine (TMB) and o-phenylenediamine (OPD), in the presence of hydrogen peroxide. In addition to the recent discoveries regarding peroxidase mimetics on Fe(3)O(4) NPs and carbon nanostructures, our findings suggest a new kind of candidate for peroxidase mimics. This may open up a new application field of CuS micro-nano structures in biodetection, biocatalysis and environmental monitoring.
硫化铜 (CuS) 凹多面体超结构 (CPSs) 已成功地在乙醇溶液中通过简单的溶剂热反应制备，而无需使用表面活性剂或模板。制备了两种典型的具有明确定义的高对称性 CuS 凹多面体，形成凹截角八面体和二十面体。研究了反应时间、温度以及不同的 Cu 离子和硫源对 CuS CPSs 形成的影响，并根据气相色谱-质谱法提出并讨论了一种可能的形成机制。更重要的是，我们首次发现 CuS CPSs 具有内在的过氧化物酶样活性，因为它们可以在过氧化氢存在下快速催化典型辣根过氧化物酶 (HRP) 底物 3,3',5,5'-四甲基联苯胺 (TMB) 和邻苯二胺 (OPD) 的氧化。除了最近在 Fe(3)O(4) NPs 和碳纳米结构上发现的过氧化物酶模拟物，我们的发现为过氧化物酶模拟物提供了一种新的候选物。这可能为 CuS 微纳结构在生物检测、生物催化和环境监测中的应用开辟了一个新的领域。
