Division of Community Oral Health Science, Department of Health Promotion, School of Dentistry, Kyushu Dental College, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Japan.
Clin Oral Investig. 2013 Mar;17(2):483-9. doi: 10.1007/s00784-012-0741-1. Epub 2012 May 3.
The objective of this study was to clarify differences in oral health status between patients who needed haemodialysis (HD) owing to diabetic nephropathy (DN) and chronic glomerulonephritis (CGN).
Ninety-eight HD patients who were 50-70 years old were selected as the study subjects [DN group (29 subjects) and CGN group (69 subjects)] to compare with 106 control subjects (control group) not undergoing HD. All HD subjects underwent oral- and systemic-related examination just before HD therapy.
The mean number of teeth present in the DN group was significantly less than in the CGN and control groups. The mean percentage of sites with bleeding on probing in the DN group was greater than in the CGN and control groups. The mean salivary flow rate in the DN and CGN groups was significantly lower compared with the control group.
The patients undergoing HD for DN were found to have fewer teeth and worse periodontal health compared with those undergoing HD for CGN and with the control subjects not undergoing HD. Furthermore, the dental and periodontal health of the patients undergoing HD for CGN was comparable to that of the controls.
For effective measures of prevention and improvement of oral health in HD patients, clinicians should be aware of the differences in the characteristics of the oral health between patients undergoing HD for DN and CGN.
本研究旨在阐明因糖尿病肾病（DN）和慢性肾小球肾炎（CGN）而需要血液透析（HD）的患者口腔健康状况的差异。
选择 98 名年龄在 50-70 岁之间的 HD 患者作为研究对象[DN 组（29 名）和 CGN 组（69 名）]，并与未接受 HD 的 106 名对照者（对照组）进行比较。所有 HD 患者在 HD 治疗前进行口腔和全身相关检查。
DN 组的平均牙齿数明显少于 CGN 组和对照组。DN 组的探诊出血位点百分比均值大于 CGN 组和对照组。DN 组和 CGN 组的唾液流率明显低于对照组。
与因 CGN 而接受 HD 的患者和未接受 HD 的对照者相比，因 DN 而接受 HD 的患者牙齿较少，牙周健康状况较差。此外，因 CGN 而接受 HD 的患者的口腔和牙周健康状况与对照组相当。
为了对 HD 患者的口腔健康进行有效的预防和改善措施，临床医生应该意识到因 DN 和 CGN 而接受 HD 的患者口腔健康特征的差异。
