Life Sciences Group, Centrum Wiskunde & Informatica, Science Park 123, 1098 XG Amsterdam, The Netherlands.
Nucleic Acids Res. 2012 Jul;40(Web Server issue):W303-9. doi: 10.1093/nar/gks362. Epub 2012 May 2.
CSA is a web server for the computation, evaluation and comprehensive comparison of pairwise protein structure alignments. Its exact alignment engine computes either optimal, top-scoring alignments or heuristic alignments with quality guarantee for the inter-residue distance-based scorings of contact map overlap, PAUL, DALI and MATRAS. These and additional, uploaded alignments are compared using a number of quality measures and intuitive visualizations. CSA brings new insight into the structural relationship of the protein pairs under investigation and is a valuable tool for studying structural similarities. It is available at http://csa.project.cwi.nl.
CSA 是一个用于计算、评估和综合比较蛋白质结构比对的网络服务器。它的精确比对引擎可以计算最优的、得分最高的比对，或者具有质量保证的启发式比对，适用于基于残基距离的接触图重叠、PAUL、DALI 和 MATRAS 的打分。这些以及其他上传的比对可以使用多种质量度量和直观的可视化方法进行比较。CSA 为研究的蛋白质对的结构关系提供了新的见解，是研究结构相似性的有用工具。它可以在 http://csa.project.cwi.nl 上获得。
